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A Useful and Sustainable Role for N-of-1 Trials in the Healthcare Ecosystem.
Selker HP, Cohen T, D'Agostino RB, Dere WH, Ghaemi SN, Honig PK, Kaitin KI, Kaplan HC, Kravitz RL, Larholt K, McElwee NE, Oye KA, Palm ME, Perfetto E, Ramanathan C, Schmid CH, Seyfert-Margolis V, Trusheim M, Eichler HG. Selker HP, et al. Among authors: cohen t. Clin Pharmacol Ther. 2022 Aug;112(2):224-232. doi: 10.1002/cpt.2425. Epub 2021 Oct 20. Clin Pharmacol Ther. 2022. PMID: 34551122 Free PMC article. Review.
Efficacy and Effectiveness Too Trials: Clinical Trial Designs to Generate Evidence on Efficacy and on Effectiveness in Wide Practice.
Selker HP, Eichler HG, Stockbridge NL, McElwee NE, Dere WH, Cohen T, Erban JK, Seyfert-Margolis VL, Honig PK, Kaitin KI, Oye KA, D'Agostino RB Sr. Selker HP, et al. Among authors: cohen t. Clin Pharmacol Ther. 2019 Apr;105(4):857-866. doi: 10.1002/cpt.1347. Epub 2019 Feb 12. Clin Pharmacol Ther. 2019. PMID: 30610746 Free PMC article.
An example of medical device-based projection of clinical trial enrollment: Use of electrocardiographic data to identify candidates for a trial in acute coronary syndromes.
Selker HP, Kwong M, Ruthazer R, Gorman S, Green G, Patchen E, Udelson JE, Smithline HA, Baumann MR, Harris PA, Shah RU, Nelson SJ, Cohen T, Jones EB, Barnewolt BA, Williams AE. Selker HP, et al. Among authors: cohen t. J Clin Transl Sci. 2018 Dec;2(6):377-383. doi: 10.1017/cts.2019.365. J Clin Transl Sci. 2018. PMID: 31404280 Free PMC article.
Efficacy of Niclosamide vs Placebo in SARS-CoV-2 Respiratory Viral Clearance, Viral Shedding, and Duration of Symptoms Among Patients With Mild to Moderate COVID-19: A Phase 2 Randomized Clinical Trial.
Cairns DM, Dulko D, Griffiths JK, Golan Y, Cohen T, Trinquart L, Price LL, Beaulac KR, Selker HP. Cairns DM, et al. Among authors: cohen t. JAMA Netw Open. 2022 Feb 1;5(2):e2144942. doi: 10.1001/jamanetworkopen.2021.44942. JAMA Netw Open. 2022. PMID: 35138402 Free PMC article. Clinical Trial.
Leveraging the Expertise of the CTSA Program to Increase the Impact and Efficiency of Clinical Trials.
Harris PA, Dunsmore SE, Atkinson JC, Benjamin DK Jr, Bernard GR, Dean JM, Dwyer JP, Ford DF, Selker HP, Waddy SP, Wiley KL, Wilkins CH, Cook SK, Burr JS, Edwards TL, Huvane J, Kennedy N, Lane K, Majkowski R, Nelson S, Palm ME, Stroud M, Thompson DD, Busacca L, Elkind MSV, Kimberly RP, Reilly MP, Hanley DF; Trial Innovation Network. Harris PA, et al. JAMA Netw Open. 2023 Oct 2;6(10):e2336470. doi: 10.1001/jamanetworkopen.2023.36470. JAMA Netw Open. 2023. PMID: 37796498 Free PMC article.
A global initiative for ecological and evolutionary hologenomics.
Leonard A; Earth Hologenome Initiative Consortium; Alberdi A. Leonard A, et al. Trends Ecol Evol. 2024 May 9:S0169-5347(24)00074-0. doi: 10.1016/j.tree.2024.03.005. Online ahead of print. Trends Ecol Evol. 2024. PMID: 38777633
Opportunities for incorporating intersectionality into biomedical informatics.
Bear Don't Walk OJ 4th, Paullada A, Everhart A, Casanova-Perez R, Cohen T, Veinot T. Bear Don't Walk OJ 4th, et al. Among authors: cohen t. J Biomed Inform. 2024 Jun;154:104653. doi: 10.1016/j.jbi.2024.104653. Epub 2024 May 10. J Biomed Inform. 2024. PMID: 38734158 Free article.
1,336 results