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An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation.
Harms M, Habib MMW, Nemska S, Nicolò A, Gilg A, Preising N, Sokkar P, Carmignani S, Raasholm M, Weidinger G, Kizilsavas G, Wagner M, Ständker L, Abadi AH, Jumaa H, Kirchhoff F, Frossard N, Sanchez-Garcia E, Münch J. Harms M, et al. Among authors: sokkar p. Acta Pharm Sin B. 2021 Sep;11(9):2694-2708. doi: 10.1016/j.apsb.2020.12.005. Epub 2020 Dec 13. Acta Pharm Sin B. 2021. PMID: 34589390 Free PMC article.
Rational prioritization strategy allows the design of macrolide derivatives that overcome antibiotic resistance.
König G, Sokkar P, Pryk N, Heinrich S, Möller D, Cimicata G, Matzov D, Dietze P, Thiel W, Bashan A, Bandow JE, Zuegg J, Yonath A, Schulz F, Sanchez-Garcia E. König G, et al. Among authors: sokkar p. Proc Natl Acad Sci U S A. 2021 Nov 16;118(46):e2113632118. doi: 10.1073/pnas.2113632118. Proc Natl Acad Sci U S A. 2021. PMID: 34750269 Free PMC article.
Solvent-Enhanced Conformational Flexibility of Cyclic Tetrapeptides.
Berger N, Wollny LJB, Sokkar P, Mittal S, Mieres-Perez J, Stoll R, Sander W, Sanchez-Garcia E. Berger N, et al. Among authors: sokkar p. Chemphyschem. 2019 Jul 2;20(13):1664-1670. doi: 10.1002/cphc.201900345. Epub 2019 Jun 13. Chemphyschem. 2019. PMID: 31045298
The Interaction Modes of Haloimidazolium Salts in Solution.
Schulz N, Sokkar P, Engelage E, Schindler S, Erdelyi M, Sanchez-Garcia E, Huber SM. Schulz N, et al. Among authors: sokkar p. Chemistry. 2018 Mar 7;24(14):3464-3473. doi: 10.1002/chem.201705032. Epub 2017 Dec 28. Chemistry. 2018. PMID: 29160593
A Multiperspective Approach to Solvent Regulation of Enzymatic Activity: HMG-CoA Reductase.
Dirkmann M, Iglesias-Fernández J, Muñoz V, Sokkar P, Rumancev C, von Gundlach A, Krenczyk O, Vöpel T, Nowack J, Schroer MA, Ebbinghaus S, Herrmann C, Rosenhahn A, Sanchez-Garcia E, Schulz F. Dirkmann M, et al. Among authors: sokkar p. Chembiochem. 2018 Jan 18;19(2):153-158. doi: 10.1002/cbic.201700596. Epub 2017 Dec 21. Chembiochem. 2018. PMID: 29139594
19 results