Macphee CH - Search Results

1

Diabetes status modifies the long-term effect of lipoprotein-associated phospholipase A2 on major coronary events.

Siddiqui MK, Smith G, St Jean P, Dawed AY, Bell S, Soto-Pedre E, Kennedy G, Carr F, Wallentin L, White H, Macphee CH, Waterworth D, Palmer CNA. Siddiqui MK, et al. Among authors: macphee ch. Diabetologia. 2022 Jan;65(1):101-112. doi: 10.1007/s00125-021-05574-5. Epub 2021 Sep 25. Diabetologia. 2022. PMID: 34562103 Free PMC article. Clinical Trial.

2

Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.

Yeo A, Li L, Warren L, Aponte J, Fraser D, King K, Johansson K, Barnes A, MacPhee C, Davies R, Chissoe S, Tarka E, O'Donoghue ML, White HD, Wallentin L, Waterworth D. Yeo A, et al. PLoS One. 2017 Jul 28;12(7):e0182115. doi: 10.1371/journal.pone.0182115. eCollection 2017. PLoS One. 2017. PMID: 28753643 Free PMC article.

3

Atherosclerotic plaque inflammation varies between vascular sites and correlates with response to inhibition of lipoprotein-associated phospholipase A2.

Fenning RS, Burgert ME, Hamamdzic D, Peyster EG, Mohler ER, Kangovi S, Jucker BM, Lenhard SC, Macphee CH, Wilensky RL. Fenning RS, et al. Among authors: macphee ch. J Am Heart Assoc. 2015 Feb 11;4(2):e001477. doi: 10.1161/JAHA.114.001477. J Am Heart Assoc. 2015. PMID: 25672369 Free PMC article.

4

The effect of lipoprotein-associated phospholipase A2 deficiency on pulmonary allergic responses in Aspergillus fumigatus sensitized mice.

Jiang Z, Fehrenbach ML, Ravaioli G, Kokalari B, Redai IG, Sheardown SA, Wilson S, Macphee C, Haczku A. Jiang Z, et al. Respir Res. 2012 Nov 12;13(1):100. doi: 10.1186/1465-9921-13-100. Respir Res. 2012. PMID: 23140447 Free PMC article.

5

Role of lipoprotein-associated phospholipase A2 in atherosclerosis: biology, epidemiology, and possible therapeutic target.

Zalewski A, Macphee C. Zalewski A, et al. Arterioscler Thromb Vasc Biol. 2005 May;25(5):923-31. doi: 10.1161/01.ATV.0000160551.21962.a7. Epub 2005 Feb 24. Arterioscler Thromb Vasc Biol. 2005. PMID: 15731492 Review.

6

Lipoprotein-associated phospholipase A(2) and atherosclerosis.

Wilensky RL, Macphee CH. Wilensky RL, et al. Among authors: macphee ch. Curr Opin Lipidol. 2009 Oct;20(5):415-20. doi: 10.1097/MOL.0b013e3283307c16. Curr Opin Lipidol. 2009. PMID: 19667981 Review.

7

Lipoprotein-associated phospholipase A2: a target directed at the atherosclerotic plaque.

Suckling KE, Macphee CH. Suckling KE, et al. Among authors: macphee ch. Expert Opin Ther Targets. 2002 Jun;6(3):309-14. doi: 10.1517/14728222.6.3.309. Expert Opin Ther Targets. 2002. PMID: 12223071 Review.

8

Lipoprotein-associated phospholipase A2 as a target of therapy.

Macphee CH, Nelson JJ, Zalewski A. Macphee CH, et al. Curr Opin Lipidol. 2005 Aug;16(4):442-6. doi: 10.1097/01.mol.0000174155.61307.5f. Curr Opin Lipidol. 2005. PMID: 15990594 Review.

9

Effect of darapladib treatment on endarterectomy carotid plaque lipoprotein-associated phospholipase A2 activity: a randomized, controlled trial.

Johnson JL, Shi Y, Snipes R, Janmohamed S, Rolfe TE, Davis B, Postle A, Macphee CH. Johnson JL, et al. Among authors: macphee ch. PLoS One. 2014 Feb 20;9(2):e89034. doi: 10.1371/journal.pone.0089034. eCollection 2014. PLoS One. 2014. PMID: 24586490 Free PMC article. Clinical Trial.

10

Lipoprotein-associated phospholipase A2: a potential therapeutic target for atherosclerosis.

Zalewski A, Macphee C, Nelson JJ. Zalewski A, et al. Curr Drug Targets Cardiovasc Haematol Disord. 2005 Dec;5(6):527-32. doi: 10.2174/156800605774962103. Curr Drug Targets Cardiovasc Haematol Disord. 2005. PMID: 16503872 Review.

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