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Discovery of Novel UDP-N-Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa.
J Med Chem. 2021 Oct 14;64(19):14377-14425. doi: 10.1021/acs.jmedchem.1c00888. Epub 2021 Sep 27.
J Med Chem. 2021.
PMID: 34569791
Imaging Mutant Huntingtin Aggregates: Development of a Potential PET Ligand.
Liu L, Prime ME, Lee MR, Khetarpal V, Brown CJ, Johnson PD, Miranda-Azpiazu P, Chen X, Clark-Frew D, Coe S, Davis R, Dickie A, Ebneth A, Esposito S, Gadouleau E, Gai X, Galan S, Green S, Greenaway C, Giles P, Halldin C, Hayes S, Herbst T, Herrmann F, Heßmann M, Jia Z, Kiselyov A, Kotey A, Krulle T, Mangette JE, Marston RW, Menta S, Mills MR, Monteagudo E, Nag S, Nibbio M, Orsatti L, Schaertl S, Scheich C, Sproston J, Stepanov V, Svedberg M, Takano A, Taylor M, Thomas W, Toth M, Vaidya D, Vanräs K, Weddell D, Wigginton I, Wityak J, Mrzljak L, Munoz-Sanjuan I, Bard JA, Dominguez C.
Liu L, et al.
J Med Chem. 2020 Aug 13;63(15):8608-8633. doi: 10.1021/acs.jmedchem.0c00955. Epub 2020 Jul 30.
J Med Chem. 2020.
PMID: 32662649
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Design and Evaluation of [18F]CHDI-650 as a Positron Emission Tomography Ligand to Image Mutant Huntingtin Aggregates.
Liu L, Johnson PD, Prime ME, Khetarpal V, Brown CJ, Anzillotti L, Bertoglio D, Chen X, Coe S, Davis R, Dickie AP, Esposito S, Gadouleau E, Giles PR, Greenaway C, Haber J, Halldin C, Haller S, Hayes S, Herbst T, Herrmann F, Heßmann M, Hsai MM, Khani Y, Kotey A, Lembo A, Mangette JE, Marriner GA, Marston RW, Mills MR, Monteagudo E, Forsberg-Morén A, Nag S, Orsatti L, Sandiego C, Schaertl S, Sproston J, Staelens S, Tookey J, Turner PA, Vecchi A, Veneziano M, Muñoz-Sanjuan I, Bard J, Dominguez C.
Liu L, et al. Among authors: dickie ap.
J Med Chem. 2023 Jan 12;66(1):641-656. doi: 10.1021/acs.jmedchem.2c01585. Epub 2022 Dec 22.
J Med Chem. 2023.
PMID: 36548390
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The pharmacokinetics and metabolism of diclofenac in chimeric humanized and murinized FRG mice.
Wilson CE, Dickie AP, Schreiter K, Wehr R, Wilson EM, Bial J, Scheer N, Wilson ID, Riley RJ.
Wilson CE, et al. Among authors: dickie ap.
Arch Toxicol. 2018 Jun;92(6):1953-1967. doi: 10.1007/s00204-018-2212-1. Epub 2018 May 2.
Arch Toxicol. 2018.
PMID: 29721588
Free article.
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The pharmacokinetics and metabolism of lumiracoxib in chimeric humanized and murinized FRG mice.
Dickie AP, Wilson CE, Schreiter K, Wehr R, Wilson EM, Bial J, Scheer N, Wilson ID, Riley RJ.
Dickie AP, et al.
Biochem Pharmacol. 2017 Jul 1;135:139-150. doi: 10.1016/j.bcp.2017.03.015. Epub 2017 Mar 27.
Biochem Pharmacol. 2017.
PMID: 28351678
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Retention-directed and selectivity controlled chromatographic resolution: Rapid post-hoc analysis of DMPK samples to achieve high-throughput LC-MS separation.
Turnpenny P, Dickie A, Malec J, McClements J.
Turnpenny P, et al.
J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Feb 1;1164:122514. doi: 10.1016/j.jchromb.2020.122514. Epub 2020 Dec 24.
J Chromatogr B Analyt Technol Biomed Life Sci. 2021.
PMID: 33477099
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Reversible C-C bond formation: solid state structure of the aldol-like addition product of adamantanone to a 1,5-diazapentadienyllithium, and its solution state retro-aldol dissociation.
Ball LJ, Dickie AP, Mair FS, Middleton DA, Pritchard RG.
Ball LJ, et al. Among authors: dickie ap.
Chem Commun (Camb). 2003 Mar 21;(6):744-5. doi: 10.1039/b211745b.
Chem Commun (Camb). 2003.
PMID: 12703802
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