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Mendelian randomisation and experimental medicine approaches to interleukin-6 as a drug target in pulmonary arterial hypertension.
Toshner M, Church C, Harbaum L, Rhodes C, Villar Moreschi SS, Liley J, Jones R, Arora A, Batai K, Desai AA, Coghlan JG, Gibbs JSR, Gor D, Gräf S, Harlow L, Hernandez-Sanchez J, Howard LS, Humbert M, Karnes J, Kiely DG, Kittles R, Knightbridge E, Lam B, Lutz KA, Nichols WC, Pauciulo MW, Pepke-Zaba J, Suntharalingam J, Soubrier F, Trembath RC, Schwantes-An TL, Wort SJ, Wilkins MR, Gaine S, Morrell NW, Corris PA; Uniphy Clinical Trials Network. Toshner M, et al. Among authors: howard ls. Eur Respir J. 2022 Mar 10;59(3):2002463. doi: 10.1183/13993003.02463-2020. Print 2022 Mar. Eur Respir J. 2022. PMID: 34588193 Free PMC article.
Emerging therapies for pulmonary arterial hypertension.
Ali O, Wharton J, Gibbs JS, Howard L, Wilkins MR. Ali O, et al. Expert Opin Investig Drugs. 2007 Jun;16(6):803-18. doi: 10.1517/13543784.16.6.803. Expert Opin Investig Drugs. 2007. PMID: 17501693 Review.
Simvastatin as a treatment for pulmonary hypertension trial.
Wilkins MR, Ali O, Bradlow W, Wharton J, Taegtmeyer A, Rhodes CJ, Ghofrani HA, Howard L, Nihoyannopoulos P, Mohiaddin RH, Gibbs JS; Simvastatin Pulmonary Hypertension Trial (SiPHT) Study Group. Wilkins MR, et al. Am J Respir Crit Care Med. 2010 May 15;181(10):1106-13. doi: 10.1164/rccm.2009111-699oc. Am J Respir Crit Care Med. 2010. PMID: 20460548 Free PMC article. Clinical Trial.
The association between tricuspid regurgitation velocity and 5-year survival in a North West London population of patients with sickle cell disease in the United Kingdom.
Cabrita IZ, Mohammed A, Layton M, Ghorashian S, Gilmore A, Cho G, Howard J, Anie KA, Desforges L, Bassett P, Grapsa J, Howard L, Mahalingam G, Dawson D, Pinto FJ, Nihoyannopoulos P, Davies SC, Gibbs JS. Cabrita IZ, et al. Br J Haematol. 2013 Aug;162(3):400-8. doi: 10.1111/bjh.12391. Epub 2013 May 29. Br J Haematol. 2013. PMID: 23713628 Free article.
Bosentan in pulmonary hypertension associated with fibrotic idiopathic interstitial pneumonia.
Corte TJ, Keir GJ, Dimopoulos K, Howard L, Corris PA, Parfitt L, Foley C, Yanez-Lopez M, Babalis D, Marino P, Maher TM, Renzoni EA, Spencer L, Elliot CA, Birring SS, O'Reilly K, Gatzoulis MA, Wells AU, Wort SJ; BPHIT Study Group. Corte TJ, et al. Am J Respir Crit Care Med. 2014 Jul 15;190(2):208-17. doi: 10.1164/rccm.201403-0446OC. Am J Respir Crit Care Med. 2014. PMID: 24937643 Free PMC article. Clinical Trial.
192 results