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A mutation in calsequestrin, CASQ2D307H, impairs Sarcoplasmic Reticulum Ca2+ handling and causes complex ventricular arrhythmias in mice.
Dirksen WP, Lacombe VA, Chi M, Kalyanasundaram A, Viatchenko-Karpinski S, Terentyev D, Zhou Z, Vedamoorthyrao S, Li N, Chiamvimonvat N, Carnes CA, Franzini-Armstrong C, Györke S, Periasamy M. Dirksen WP, et al. Among authors: li n. Cardiovasc Res. 2007 Jul 1;75(1):69-78. doi: 10.1016/j.cardiores.2007.03.002. Epub 2007 Mar 12. Cardiovasc Res. 2007. PMID: 17449018 Free PMC article.
Upregulation of adenosine A1 receptors facilitates sinoatrial node dysfunction in chronic canine heart failure by exacerbating nodal conduction abnormalities revealed by novel dual-sided intramural optical mapping.
Lou Q, Hansen BJ, Fedorenko O, Csepe TA, Kalyanasundaram A, Li N, Hage LT, Glukhov AV, Billman GE, Weiss R, Mohler PJ, Györke S, Biesiadecki BJ, Carnes CA, Fedorov VV. Lou Q, et al. Among authors: li n. Circulation. 2014 Jul 22;130(4):315-24. doi: 10.1161/CIRCULATIONAHA.113.007086. Epub 2014 May 16. Circulation. 2014. PMID: 24838362 Free PMC article.
Atrial fibrillation driven by micro-anatomic intramural re-entry revealed by simultaneous sub-epicardial and sub-endocardial optical mapping in explanted human hearts.
Hansen BJ, Zhao J, Csepe TA, Moore BT, Li N, Jayne LA, Kalyanasundaram A, Lim P, Bratasz A, Powell KA, Simonetti OP, Higgins RS, Kilic A, Mohler PJ, Janssen PM, Weiss R, Hummel JD, Fedorov VV. Hansen BJ, et al. Among authors: li n. Eur Heart J. 2015 Sep 14;36(35):2390-401. doi: 10.1093/eurheartj/ehv233. Epub 2015 Jun 8. Eur Heart J. 2015. PMID: 26059724 Free PMC article.
Molecular Mapping of Sinoatrial Node HCN Channel Expression in the Human Heart.
Li N, Csepe TA, Hansen BJ, Dobrzynski H, Higgins RS, Kilic A, Mohler PJ, Janssen PM, Rosen MR, Biesiadecki BJ, Fedorov VV. Li N, et al. Circ Arrhythm Electrophysiol. 2015 Oct;8(5):1219-27. doi: 10.1161/CIRCEP.115.003070. Epub 2015 Aug 24. Circ Arrhythm Electrophysiol. 2015. PMID: 26304511 Free PMC article.
Human sinoatrial node structure: 3D microanatomy of sinoatrial conduction pathways.
Csepe TA, Zhao J, Hansen BJ, Li N, Sul LV, Lim P, Wang Y, Simonetti OP, Kilic A, Mohler PJ, Janssen PM, Fedorov VV. Csepe TA, et al. Among authors: li n. Prog Biophys Mol Biol. 2016 Jan;120(1-3):164-78. doi: 10.1016/j.pbiomolbio.2015.12.011. Epub 2015 Dec 30. Prog Biophys Mol Biol. 2016. PMID: 26743207 Free PMC article.
Rationally engineered Troponin C modulates in vivo cardiac function and performance in health and disease.
Shettigar V, Zhang B, Little SC, Salhi HE, Hansen BJ, Li N, Zhang J, Roof SR, Ho HT, Brunello L, Lerch JK, Weisleder N, Fedorov VV, Accornero F, Rafael-Fortney JA, Gyorke S, Janssen PM, Biesiadecki BJ, Ziolo MT, Davis JP. Shettigar V, et al. Among authors: li n. Nat Commun. 2016 Feb 24;7:10794. doi: 10.1038/ncomms10794. Nat Commun. 2016. PMID: 26908229 Free PMC article.
Two-Pore K+ Channel TREK-1 Regulates Sinoatrial Node Membrane Excitability.
Unudurthi SD, Wu X, Qian L, Amari F, Onal B, Li N, Makara MA, Smith SA, Snyder J, Fedorov VV, Coppola V, Anderson ME, Mohler PJ, Hund TJ. Unudurthi SD, et al. Among authors: li n. J Am Heart Assoc. 2016 Apr 20;5(4):e002865. doi: 10.1161/JAHA.115.002865. J Am Heart Assoc. 2016. PMID: 27098968 Free PMC article.
Adenosine-Induced Atrial Fibrillation: Localized Reentrant Drivers in Lateral Right Atria due to Heterogeneous Expression of Adenosine A1 Receptors and GIRK4 Subunits in the Human Heart.
Li N, Csepe TA, Hansen BJ, Sul LV, Kalyanasundaram A, Zakharkin SO, Zhao J, Guha A, Van Wagoner DR, Kilic A, Mohler PJ, Janssen PM, Biesiadecki BJ, Hummel JD, Weiss R, Fedorov VV. Li N, et al. Circulation. 2016 Aug 9;134(6):486-98. doi: 10.1161/CIRCULATIONAHA.115.021165. Epub 2016 Jul 26. Circulation. 2016. PMID: 27462069 Free PMC article.
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