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Structure-based classification of tauopathies.
Shi Y, Zhang W, Yang Y, Murzin AG, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, Yoshida M, Tanaka H, Kakita A, Ikeuchi T, Robinson AC, Mann DMA, Kovacs GG, Revesz T, Ghetti B, Hasegawa M, Goedert M, Scheres SHW. Shi Y, et al. Among authors: scheres shw. Nature. 2021 Oct;598(7880):359-363. doi: 10.1038/s41586-021-03911-7. Epub 2021 Sep 29. Nature. 2021. PMID: 34588692 Free PMC article.
Three-dimensional structure of human γ-secretase.
Lu P, Bai XC, Ma D, Xie T, Yan C, Sun L, Yang G, Zhao Y, Zhou R, Scheres SHW, Shi Y. Lu P, et al. Among authors: scheres shw. Nature. 2014 Aug 14;512(7513):166-170. doi: 10.1038/nature13567. Epub 2014 Jun 29. Nature. 2014. PMID: 25043039 Free PMC article.
An atomic structure of human γ-secretase.
Bai XC, Yan C, Yang G, Lu P, Ma D, Sun L, Zhou R, Scheres SHW, Shi Y. Bai XC, et al. Among authors: scheres shw. Nature. 2015 Sep 10;525(7568):212-217. doi: 10.1038/nature14892. Epub 2015 Aug 17. Nature. 2015. PMID: 26280335 Free PMC article.
Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Å resolution.
Nguyen THD, Galej WP, Bai XC, Oubridge C, Newman AJ, Scheres SHW, Nagai K. Nguyen THD, et al. Among authors: scheres shw. Nature. 2016 Feb 18;530(7590):298-302. doi: 10.1038/nature16940. Epub 2016 Feb 1. Nature. 2016. PMID: 26829225 Free PMC article.
Cryo-EM structures of tau filaments from Alzheimer's disease.
Fitzpatrick AWP, Falcon B, He S, Murzin AG, Murshudov G, Garringer HJ, Crowther RA, Ghetti B, Goedert M, Scheres SHW. Fitzpatrick AWP, et al. Among authors: scheres shw. Nature. 2017 Jul 13;547(7662):185-190. doi: 10.1038/nature23002. Epub 2017 Jul 5. Nature. 2017. PMID: 28678775 Free PMC article.
Structures of filaments from Pick's disease reveal a novel tau protein fold.
Falcon B, Zhang W, Murzin AG, Murshudov G, Garringer HJ, Vidal R, Crowther RA, Ghetti B, Scheres SHW, Goedert M. Falcon B, et al. Among authors: scheres shw. Nature. 2018 Sep;561(7721):137-140. doi: 10.1038/s41586-018-0454-y. Epub 2018 Aug 29. Nature. 2018. PMID: 30158706 Free PMC article.
138 results