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Blood and immune development in human fetal bone marrow and Down syndrome.
Jardine L, Webb S, Goh I, Quiroga Londoño M, Reynolds G, Mather M, Olabi B, Stephenson E, Botting RA, Horsfall D, Engelbert J, Maunder D, Mende N, Murnane C, Dann E, McGrath J, King H, Kucinski I, Queen R, Carey CD, Shrubsole C, Poyner E, Acres M, Jones C, Ness T, Coulthard R, Elliott N, O'Byrne S, Haltalli MLR, Lawrence JE, Lisgo S, Balogh P, Meyer KB, Prigmore E, Ambridge K, Jain MS, Efremova M, Pickard K, Creasey T, Bacardit J, Henderson D, Coxhead J, Filby A, Hussain R, Dixon D, McDonald D, Popescu DM, Kowalczyk MS, Li B, Ashenberg O, Tabaka M, Dionne D, Tickle TL, Slyper M, Rozenblatt-Rosen O, Regev A, Behjati S, Laurenti E, Wilson NK, Roy A, Göttgens B, Roberts I, Teichmann SA, Haniffa M. Jardine L, et al. Among authors: kucinski i. Nature. 2021 Oct;598(7880):327-331. doi: 10.1038/s41586-021-03929-x. Epub 2021 Sep 29. Nature. 2021. PMID: 34588693 Free PMC article.
Pharmacological inhibition of METTL3 impacts specific haematopoietic lineages.
Sturgess K, Yankova E, Vijayabaskar MS, Isobe T, Rak J, Kucinski I, Barile M, Webster NA, Eleftheriou M, Hannah R, Gozdecka M, Vassiliou G, Rausch O, Wilson NK, Göttgens B, Tzelepis K. Sturgess K, et al. Among authors: kucinski i. Leukemia. 2023 Oct;37(10):2133-2137. doi: 10.1038/s41375-023-01965-2. Epub 2023 Jul 19. Leukemia. 2023. PMID: 37464070 Free PMC article. No abstract available.
CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation.
Hsu J, Huang HT, Lee CT, Choudhuri A, Wilson NK, Abraham BJ, Moignard V, Kucinski I, Yu S, Hyde RK, Tober J, Cai X, Li Y, Guo Y, Yang S, Superdock M, Trompouki E, Calero-Nieto FJ, Ghamari A, Jiang J, Gao P, Gao L, Nguyen V, Robertson AL, Durand EM, Kathrein KL, Aifantis I, Gerber SA, Tong W, Tan K, Cantor AB, Zhou Y, Liu PP, Young RA, Göttgens B, Speck NA, Zon LI. Hsu J, et al. Among authors: kucinski i. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23626-23635. doi: 10.1073/pnas.2003228117. Epub 2020 Sep 3. Proc Natl Acad Sci U S A. 2020. PMID: 32883883 Free PMC article.
22 results