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An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation.
Harms M, Habib MMW, Nemska S, Nicolò A, Gilg A, Preising N, Sokkar P, Carmignani S, Raasholm M, Weidinger G, Kizilsavas G, Wagner M, Ständker L, Abadi AH, Jumaa H, Kirchhoff F, Frossard N, Sanchez-Garcia E, Münch J. Harms M, et al. Among authors: jumaa h. Acta Pharm Sin B. 2021 Sep;11(9):2694-2708. doi: 10.1016/j.apsb.2020.12.005. Epub 2020 Dec 13. Acta Pharm Sin B. 2021. PMID: 34589390 Free PMC article.
Rheumatoid factor IgM autoantibodies control IgG homeostasis.
Nicolò A, Amendt T, El Ayoubi O, Young M, Finzel S, Senel M, Voll RE, Jumaa H. Nicolò A, et al. Among authors: jumaa h. Front Immunol. 2022 Oct 21;13:1016263. doi: 10.3389/fimmu.2022.1016263. eCollection 2022. Front Immunol. 2022. PMID: 36341420 Free PMC article.
B cell receptor isotypes differentially associate with cell signaling, kinetics, and outcome in chronic lymphocytic leukemia.
Mazzarello AN, Gentner-Göbel E, Dühren-von Minden M, Tarasenko TN, Nicolò A, Ferrer G, Vergani S, Liu Y, Bagnara D, Rai KR, Burger JA, McGuire PJ, Maity PC, Jumaa H, Chiorazzi N. Mazzarello AN, et al. Among authors: jumaa h. J Clin Invest. 2022 Jan 18;132(2):e149308. doi: 10.1172/JCI149308. J Clin Invest. 2022. PMID: 34813501 Free PMC article.
Autoreactive antibodies control blood glucose by regulating insulin homeostasis.
Amendt T, Allies G, Nicolò A, El Ayoubi O, Young M, Röszer T, Setz CS, Warnatz K, Jumaa H. Amendt T, et al. Among authors: jumaa h. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2115695119. doi: 10.1073/pnas.2115695119. Proc Natl Acad Sci U S A. 2022. PMID: 35131852 Free PMC article.
IGLV3-21*01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling.
Maity PC, Bilal M, Koning MT, Young M, van Bergen CAM, Renna V, Nicolò A, Datta M, Gentner-Göbel E, Barendse RS, Somers SF, de Groen RAL, Vermaat JSP, Steinbrecher D, Schneider C, Tausch E, Bittolo T, Bomben R, Mazzarello AN, Del Poeta G, Kroes WGM, van Wezel JT, Imkeller K, Busse CE, Degano M, Bakchoul T, Schulz AR, Mei H, Ghia P, Kotta K, Stamatopoulos K, Wardemann H, Zucchetto A, Chiorazzi N, Gattei V, Stilgenbauer S, Veelken H, Jumaa H. Maity PC, et al. Among authors: jumaa h. Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4320-4327. doi: 10.1073/pnas.1913810117. Epub 2020 Feb 11. Proc Natl Acad Sci U S A. 2020. PMID: 32047037 Free PMC article.
Primary Immune Responses and Affinity Maturation Are Controlled by IgD.
Amendt T, Ayoubi OE, Linder AT, Allies G, Young M, Setz CS, Jumaa H. Amendt T, et al. Among authors: jumaa h. Front Immunol. 2021 Aug 9;12:709240. doi: 10.3389/fimmu.2021.709240. eCollection 2021. Front Immunol. 2021. PMID: 34434193 Free PMC article.
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