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Page 1
Epithelial X-Box Binding Protein 1 Coordinates Tumor Protein p53-Driven DNA Damage Responses and Suppression of Intestinal Carcinogenesis.
Welz L, Kakavand N, Hang X, Laue G, Ito G, Silva MG, Plattner C, Mishra N, Tengen F, Ogris C, Jesinghaus M, Wottawa F, Arnold P, Kaikkonen L, Stengel S, Tran F, Das S, Kaser A, Trajanoski Z, Blumberg R, Roecken C, Saur D, Tschurtschenthaler M, Schreiber S, Rosenstiel P, Aden K. Welz L, et al. Among authors: saur d. Gastroenterology. 2022 Jan;162(1):223-237.e11. doi: 10.1053/j.gastro.2021.09.057. Epub 2021 Sep 30. Gastroenterology. 2022. PMID: 34599932 Free PMC article.
E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex.
von Burstin J, Eser S, Paul MC, Seidler B, Brandl M, Messer M, von Werder A, Schmidt A, Mages J, Pagel P, Schnieke A, Schmid RM, Schneider G, Saur D. von Burstin J, et al. Among authors: saur d. Gastroenterology. 2009 Jul;137(1):361-71, 371.e1-5. doi: 10.1053/j.gastro.2009.04.004. Epub 2009 Apr 9. Gastroenterology. 2009. PMID: 19362090
Morphology Matters: A Critical Reappraisal of the Clinical Relevance of Morphologic Criteria From the 2019 WHO Classification in a Large Colorectal Cancer Cohort Comprising 1004 Cases.
Jesinghaus M, Schmitt M, Lang C, Reiser M, Scheiter A, Konukiewitz B, Steiger K, Silva M, Tschurtschenthaler M, Lange S, Foersch S, Becker KF, Saur D, Friess H, Halfter K, Engel J, Boxberg M, Pfarr N, Wilhelm D, Weichert W. Jesinghaus M, et al. Among authors: saur d. Am J Surg Pathol. 2021 Jul 1;45(7):969-978. doi: 10.1097/PAS.0000000000001692. Am J Surg Pathol. 2021. PMID: 34105518
Genetic Screens Identify a Context-Specific PI3K/p27Kip1 Node Driving Extrahepatic Biliary Cancer.
Falcomatà C, Bärthel S, Ulrich A, Diersch S, Veltkamp C, Rad L, Boniolo F, Solar M, Steiger K, Seidler B, Zukowska M, Madej J, Wang M, Öllinger R, Maresch R, Barenboim M, Eser S, Tschurtschenthaler M, Mehrabi A, Roessler S, Goeppert B, Kind A, Schnieke A, Robles MS, Bradley A, Schmid RM, Schmidt-Supprian M, Reichert M, Weichert W, Sansom OJ, Morton JP, Rad R, Schneider G, Saur D. Falcomatà C, et al. Among authors: saur d. Cancer Discov. 2021 Dec 1;11(12):3158-3177. doi: 10.1158/2159-8290.CD-21-0209. Cancer Discov. 2021. PMID: 34282029 Free PMC article.
Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment.
Falcomatà C, Bärthel S, Widholz SA, Schneeweis C, Montero JJ, Toska A, Mir J, Kaltenbacher T, Heetmeyer J, Swietlik JJ, Cheng JY, Teodorescu B, Reichert O, Schmitt C, Grabichler K, Coluccio A, Boniolo F, Veltkamp C, Zukowska M, Vargas AA, Paik WH, Jesinghaus M, Steiger K, Maresch R, Öllinger R, Ammon T, Baranov O, Robles MS, Rechenberger J, Kuster B, Meissner F, Reichert M, Flossdorf M, Rad R, Schmidt-Supprian M, Schneider G, Saur D. Falcomatà C, et al. Among authors: saur d. Nat Cancer. 2022 Mar;3(3):318-336. doi: 10.1038/s43018-021-00326-1. Epub 2022 Jan 31. Nat Cancer. 2022. PMID: 35122074 Free PMC article.
Comparative Study of the Role of Interepithelial Mucosal Mast Cells in the Context of Intestinal Adenoma-Carcinoma Progression.
Groll T, Silva M, Sarker RSJ, Tschurtschenthaler M, Schnalzger T, Mogler C, Denk D, Schölch S, Schraml BU, Ruland J, Rad R, Saur D, Weichert W, Jesinghaus M, Matiasek K, Steiger K. Groll T, et al. Among authors: saur d. Cancers (Basel). 2022 Apr 30;14(9):2248. doi: 10.3390/cancers14092248. Cancers (Basel). 2022. PMID: 35565377 Free PMC article.
Non-canonical functions of SNAIL drive context-specific cancer progression.
Paul MC, Schneeweis C, Falcomatà C, Shan C, Rossmeisl D, Koutsouli S, Klement C, Zukowska M, Widholz SA, Jesinghaus M, Heuermann KK, Engleitner T, Seidler B, Sleiman K, Steiger K, Tschurtschenthaler M, Walter B, Weidemann SA, Pietsch R, Schnieke A, Schmid RM, Robles MS, Andrieux G, Boerries M, Rad R, Schneider G, Saur D. Paul MC, et al. Among authors: saur d. Nat Commun. 2023 Mar 7;14(1):1201. doi: 10.1038/s41467-023-36505-0. Nat Commun. 2023. PMID: 36882420 Free PMC article.
Cross talk between stimulated NF-kappaB and the tumor suppressor p53.
Schneider G, Henrich A, Greiner G, Wolf V, Lovas A, Wieczorek M, Wagner T, Reichardt S, von Werder A, Schmid RM, Weih F, Heinzel T, Saur D, Krämer OH. Schneider G, et al. Among authors: saur d. Oncogene. 2010 May 13;29(19):2795-806. doi: 10.1038/onc.2010.46. Epub 2010 Mar 1. Oncogene. 2010. PMID: 20190799
335 results