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Epithelial X-Box Binding Protein 1 Coordinates Tumor Protein p53-Driven DNA Damage Responses and Suppression of Intestinal Carcinogenesis.
Welz L, Kakavand N, Hang X, Laue G, Ito G, Silva MG, Plattner C, Mishra N, Tengen F, Ogris C, Jesinghaus M, Wottawa F, Arnold P, Kaikkonen L, Stengel S, Tran F, Das S, Kaser A, Trajanoski Z, Blumberg R, Roecken C, Saur D, Tschurtschenthaler M, Schreiber S, Rosenstiel P, Aden K. Welz L, et al. Among authors: silva mg. Gastroenterology. 2022 Jan;162(1):223-237.e11. doi: 10.1053/j.gastro.2021.09.057. Epub 2021 Sep 30. Gastroenterology. 2022. PMID: 34599932 Free PMC article.
Morphology Matters: A Critical Reappraisal of the Clinical Relevance of Morphologic Criteria From the 2019 WHO Classification in a Large Colorectal Cancer Cohort Comprising 1004 Cases.
Jesinghaus M, Schmitt M, Lang C, Reiser M, Scheiter A, Konukiewitz B, Steiger K, Silva M, Tschurtschenthaler M, Lange S, Foersch S, Becker KF, Saur D, Friess H, Halfter K, Engel J, Boxberg M, Pfarr N, Wilhelm D, Weichert W. Jesinghaus M, et al. Am J Surg Pathol. 2021 Jul 1;45(7):969-978. doi: 10.1097/PAS.0000000000001692. Am J Surg Pathol. 2021. PMID: 34105518
Loss of CDX2 in colorectal cancer is associated with histopathologic subtypes and microsatellite instability but is prognostically inferior to hematoxylin-eosin-based morphologic parameters from the WHO classification.
Konukiewitz B, Schmitt M, Silva M, Pohl J, Lang C, Steiger K, Halfter K, Engel J, Schlitter AM, Boxberg M, Pfarr N, Wilhelm D, Foersch S, Tschurtschenthaler M, Weichert W, Jesinghaus M. Konukiewitz B, et al. Br J Cancer. 2021 Dec;125(12):1632-1646. doi: 10.1038/s41416-021-01553-0. Epub 2021 Oct 6. Br J Cancer. 2021. PMID: 34616012 Free PMC article.
Microbiota and Colorectal Cancer: From Gut to Bedside.
Silva M, Brunner V, Tschurtschenthaler M. Silva M, et al. Front Pharmacol. 2021 Sep 30;12:760280. doi: 10.3389/fphar.2021.760280. eCollection 2021. Front Pharmacol. 2021. PMID: 34658896 Free PMC article. Review.
XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells.
Wahida A, Müller M, Hiergeist A, Popper B, Steiger K, Branca C, Tschurtschenthaler M, Engleitner T, Donakonda S, De Coninck J, Öllinger R, Pfautsch MK, Müller N, Silva M, Usluer S, Thiele Orberg E, Böttcher JP, Pfarr N, Anton M, Slotta-Huspenina JB, Nerlich AG, Madl T, Basic M, Bleich A, Berx G, Ruland J, Knolle PA, Rad R, Adolph TE, Vandenabeele P, Kanegane H, Gessner A, Jost PJ, Yabal M. Wahida A, et al. Sci Immunol. 2021 Nov 5;6(65):eabf7235. doi: 10.1126/sciimmunol.abf7235. Epub 2021 Nov 5. Sci Immunol. 2021. PMID: 34739338
Loss of SATB2 Occurs More Frequently Than CDX2 Loss in Colorectal Carcinoma and Identifies Particularly Aggressive Cancers in High-Risk Subgroups.
Schmitt M, Silva M, Konukiewitz B, Lang C, Steiger K, Halfter K, Engel J, Jank P, Pfarr N, Wilhelm D, Foersch S, Denkert C, Tschurtschenthaler M, Weichert W, Jesinghaus M. Schmitt M, et al. Cancers (Basel). 2021 Dec 7;13(24):6177. doi: 10.3390/cancers13246177. Cancers (Basel). 2021. PMID: 34944797 Free PMC article.
Post-neoadjuvant assessment of tumour budding according to ITBCC subgroups delivers stage- and regression-grade independent prognostic information in intestinal-type gastric adenocarcinoma.
Jesinghaus M, Herz AL, Kohlruss M, Silva M, Grass A, Lange S, Novotny A, Ott K, Schmidt T, Gaida M, Hapfelmeier A, Denkert C, Weichert W, Keller G. Jesinghaus M, et al. J Pathol Clin Res. 2022 Sep;8(5):448-457. doi: 10.1002/cjp2.284. Epub 2022 Jun 17. J Pathol Clin Res. 2022. PMID: 35715937 Free PMC article.
Novel Tumor Organoid-Based Mouse Model to Study Image Guided Radiation Therapy of Rectal Cancer After Noninvasive and Precise Endoscopic Implantation.
Felchle H, Brunner V, Groll T, Walther CN, Nefzger SM, Zaurito AE, Silva MG, Gissibl J, Topping GJ, Lansink Rotgerink L, Saur D, Steiger K, Combs SE, Tschurtschenthaler M, Fischer JC. Felchle H, et al. Among authors: silva mg. Int J Radiat Oncol Biol Phys. 2024 Mar 15;118(4):1094-1104. doi: 10.1016/j.ijrobp.2023.10.008. Epub 2023 Oct 22. Int J Radiat Oncol Biol Phys. 2024. PMID: 37875245 Free article.
578 results