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Human islet T cells are highly reactive to preproinsulin in type 1 diabetes.
Anderson AM, Landry LG, Alkanani AA, Pyle L, Powers AC, Atkinson MA, Mathews CE, Roep BO, Michels AW, Nakayama M. Anderson AM, et al. Among authors: pyle l. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2107208118. doi: 10.1073/pnas.2107208118. Proc Natl Acad Sci U S A. 2021. PMID: 34611019 Free PMC article.
Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes.
Ostrov DA, Alkanani A, McDaniel KA, Case S, Baschal EE, Pyle L, Ellis S, Pöllinger B, Seidl KJ, Shah VN, Garg SK, Atkinson MA, Gottlieb PA, Michels AW. Ostrov DA, et al. Among authors: pyle l. J Clin Invest. 2018 May 1;128(5):1888-1902. doi: 10.1172/JCI97739. Epub 2018 Apr 3. J Clin Invest. 2018. PMID: 29438107 Free PMC article.
T-cell responses to hybrid insulin peptides prior to type 1 diabetes development.
Mitchell AM, Alkanani AA, McDaniel KA, Pyle L, Waugh K, Steck AK, Nakayama M, Yu L, Gottlieb PA, Rewers MJ, Michels AW. Mitchell AM, et al. Among authors: pyle l. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2019129118. doi: 10.1073/pnas.2019129118. Proc Natl Acad Sci U S A. 2021. PMID: 33542101 Free PMC article.
Analysis of Human Leukocyte Antigen DR Alleles, Immune-Related Adverse Events, and Survival Associated With Immune Checkpoint Inhibitor Use Among Patients With Advanced Malignant Melanoma.
Akturk HK, Couts KL, Baschal EE, Karakus KE, Van Gulick RJ, Turner JA, Pyle L, Robinson WA, Michels AW. Akturk HK, et al. Among authors: pyle l. JAMA Netw Open. 2022 Dec 1;5(12):e2246400. doi: 10.1001/jamanetworkopen.2022.46400. JAMA Netw Open. 2022. PMID: 36512357 Free PMC article.
361 results