Chen T - Search Results

1

Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs.

Min J, Mayasundari A, Keramatnia F, Jonchere B, Yang SW, Jarusiewicz J, Actis M, Das S, Young B, Slavish J, Yang L, Li Y, Fu X, Garrett SH, Yun MK, Li Z, Nithianantham S, Chai S, Chen T, Shelat A, Lee RE, Nishiguchi G, White SW, Roussel MF, Potts PR, Fischer M, Rankovic Z. Min J, et al. Among authors: chen t. Angew Chem Int Ed Engl. 2021 Dec 13;60(51):26663-26670. doi: 10.1002/anie.202108848. Epub 2021 Nov 16. Angew Chem Int Ed Engl. 2021. PMID: 34614283 Free PMC article.

2

Modulation of pantothenate kinase 3 activity by small molecules that interact with the substrate/allosteric regulatory domain.

Leonardi R, Zhang YM, Yun MK, Zhou R, Zeng FY, Lin W, Cui J, Chen T, Rock CO, White SW, Jackowski S. Leonardi R, et al. Among authors: chen t. Chem Biol. 2010 Aug 27;17(8):892-902. doi: 10.1016/j.chembiol.2010.06.006. Chem Biol. 2010. PMID: 20797618 Free PMC article.

3

Structure-activity relationships of substituted 1-pyridyl-2-phenyl-1,2-ethanediones: potent, selective carboxylesterase inhibitors.

Young BM, Hyatt JL, Bouck DC, Chen T, Hanumesh P, Price J, Boyd VA, Potter PM, Webb TR. Young BM, et al. Among authors: chen t. J Med Chem. 2010 Dec 23;53(24):8709-15. doi: 10.1021/jm101101q. Epub 2010 Nov 24. J Med Chem. 2010. PMID: 21105730 Free PMC article.

4

A high-content screen identifies inhibitors of nuclear export of forkhead transcription factors.

Bouck DC, Shu P, Cui J, Shelat A, Chen T. Bouck DC, et al. Among authors: chen t. J Biomol Screen. 2011 Apr;16(4):394-404. doi: 10.1177/1087057110397889. J Biomol Screen. 2011. PMID: 21471460 Free PMC article.

5

An automated approach to efficiently reformat a large collection of compounds.

Cui J, Chai SC, Shelat AA, Guy RK, Chen T. Cui J, et al. Among authors: chen t. Curr Chem Genomics. 2011;5:42-7. doi: 10.2174/1875397301105010042. Epub 2011 Jul 22. Curr Chem Genomics. 2011. PMID: 21804905 Free PMC article.

6

Development of a pterin-based fluorescent probe for screening dihydropteroate synthase.

Zhao Y, Hammoudeh D, Lin W, Das S, Yun MK, Li Z, Griffith E, Chen T, White SW, Lee RE. Zhao Y, et al. Among authors: chen t. Bioconjug Chem. 2011 Oct 19;22(10):2110-7. doi: 10.1021/bc200346e. Epub 2011 Sep 30. Bioconjug Chem. 2011. PMID: 21916405 Free PMC article.

7

Role of CAR and PXR in xenobiotic sensing and metabolism.

Wang YM, Ong SS, Chai SC, Chen T. Wang YM, et al. Among authors: chen t. Expert Opin Drug Metab Toxicol. 2012 Jul;8(7):803-17. doi: 10.1517/17425255.2012.685237. Epub 2012 May 3. Expert Opin Drug Metab Toxicol. 2012. PMID: 22554043 Free PMC article. Review.

8

Identification of small molecule activators of BMP signaling.

Vrijens K, Lin W, Cui J, Farmer D, Low J, Pronier E, Zeng FY, Shelat AA, Guy K, Taylor MR, Chen T, Roussel MF. Vrijens K, et al. Among authors: chen t. PLoS One. 2013;8(3):e59045. doi: 10.1371/journal.pone.0059045. Epub 2013 Mar 19. PLoS One. 2013. PMID: 23527084 Free PMC article.

9

A timetable organizer for the planning and implementation of screenings in manual or semi-automation mode.

Goktug AN, Chai SC, Chen T. Goktug AN, et al. Among authors: chen t. J Biomol Screen. 2013 Sep;18(8):938-42. doi: 10.1177/1087057113487556. Epub 2013 May 7. J Biomol Screen. 2013. PMID: 23653394 Free PMC article.

10

Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1.

Wang YM, Lin W, Chai SC, Wu J, Ong SS, Schuetz EG, Chen T. Wang YM, et al. Among authors: chen t. Toxicol Appl Pharmacol. 2013 Oct 1;272(1):96-107. doi: 10.1016/j.taap.2013.05.014. Epub 2013 May 22. Toxicol Appl Pharmacol. 2013. PMID: 23707768 Free PMC article.

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