Issa F - Search Results

1

Therapeutically expanded human regulatory T-cells are super-suppressive due to HIF1A induced expression of CD73.

Jarvis LB, Rainbow DB, Coppard V, Howlett SK, Georgieva Z, Davies JL, Mullay HK, Hester J, Ashmore T, Van Den Bosch A, Grist JT, Coles AJ, Mousa HS, Pluchino S, Mahbubani KT, Griffin JL, Saeb-Parsy K, Issa F, Peruzzotti-Jametti L, Wicker LS, Jones JL. Jarvis LB, et al. Among authors: issa f. Commun Biol. 2021 Oct 14;4(1):1186. doi: 10.1038/s42003-021-02721-x. Commun Biol. 2021. PMID: 34650224 Free PMC article.

2

Ex vivo-expanded human regulatory T cells prevent the rejection of skin allografts in a humanized mouse model.

Issa F, Hester J, Goto R, Nadig SN, Goodacre TE, Wood K. Issa F, et al. Transplantation. 2010 Dec 27;90(12):1321-7. doi: 10.1097/TP.0b013e3181ff8772. Transplantation. 2010. PMID: 21048528 Free PMC article.

3

Multiple unit pooled umbilical cord blood is a viable source of therapeutic regulatory T cells.

Milward K, Issa F, Hester J, Figueroa-Tentori D, Madrigal A, Wood KJ. Milward K, et al. Among authors: issa f. Transplantation. 2013 Jan 15;95(1):85-93. doi: 10.1097/TP.0b013e31827722ed. Transplantation. 2013. PMID: 23263503 Free PMC article.

4

Homing of regulatory T cells to human skin is important for the prevention of alloimmune-mediated pathology in an in vivo cellular therapy model.

Issa F, Hester J, Milward K, Wood KJ. Issa F, et al. PLoS One. 2012;7(12):e53331. doi: 10.1371/journal.pone.0053331. Epub 2012 Dec 31. PLoS One. 2012. PMID: 23300911 Free PMC article.

5

Understanding Stem Cell Immunogenicity in Therapeutic Applications.

Wood KJ, Issa F, Hester J. Wood KJ, et al. Among authors: issa f. Trends Immunol. 2016 Jan;37(1):5-16. doi: 10.1016/j.it.2015.11.005. Epub 2015 Dec 11. Trends Immunol. 2016. PMID: 26687737 Review.

6

Selective blockade of CD28 on human T cells facilitates regulation of alloimmune responses.

Zaitsu M, Issa F, Hester J, Vanhove B, Wood KJ. Zaitsu M, et al. Among authors: issa f. JCI Insight. 2017 Oct 5;2(19):e89381. doi: 10.1172/jci.insight.89381. JCI Insight. 2017. PMID: 28978798 Free PMC article.

7

Regulatory T cells for tolerance.

Kawai K, Uchiyama M, Hester J, Wood K, Issa F. Kawai K, et al. Among authors: issa f. Hum Immunol. 2018 May;79(5):294-303. doi: 10.1016/j.humimm.2017.12.013. Epub 2017 Dec 27. Hum Immunol. 2018. PMID: 29288698 Review.

8

Deciphering the Contribution of γδ T Cells to Outcomes in Transplantation.

McCallion O, Hester J, Issa F. McCallion O, et al. Among authors: issa f. Transplantation. 2018 Dec;102(12):1983-1993. doi: 10.1097/TP.0000000000002335. Transplantation. 2018. PMID: 29994977 Free PMC article.

9

Transiently Activated Human Regulatory T Cells Upregulate BCL-XL Expression and Acquire a Functional Advantage in vivo.

Issa F, Milward K, Goto R, Betts G, Wood KJ, Hester J. Issa F, et al. Front Immunol. 2019 Apr 24;10:889. doi: 10.3389/fimmu.2019.00889. eCollection 2019. Front Immunol. 2019. PMID: 31068951 Free PMC article.

10

Systemic silencing of PHD2 causes reversible immune regulatory dysfunction.

Yamamoto A, Hester J, Macklin PS, Kawai K, Uchiyama M, Biggs D, Bishop T, Bull K, Cheng X, Cawthorne E, Coleman ML, Crockford TL, Davies B, Dow LE, Goldin R, Kranc K, Kudo H, Lawson H, McAuliffe J, Milward K, Scudamore CL, Soilleux E, Issa F, Ratcliffe PJ, Pugh CW. Yamamoto A, et al. Among authors: issa f. J Clin Invest. 2019 Jun 4;129(9):3640-3656. doi: 10.1172/JCI124099. J Clin Invest. 2019. PMID: 31162141 Free PMC article.

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