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Genome-wide analysis identifies gallstone-susceptibility loci including genes regulating gastrointestinal motility.
Fairfield CJ, Drake TM, Pius R, Bretherick AD, Campbell A, Clark DW, Fallowfield JA, Hayward C, Henderson NC, Iakovliev A, Joshi PK, Mills NL, Porteous DJ, Ramachandran P, Semple RK, Shaw CA, Sudlow CLW, Timmers PRHJ, Wilson JF, Wigmore SJ, Spiliopoulou A, Harrison EM. Fairfield CJ, et al. Among authors: ramachandran p. Hepatology. 2022 May;75(5):1081-1094. doi: 10.1002/hep.32199. Epub 2021 Dec 10. Hepatology. 2022. PMID: 34651315
Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis.
Ramachandran P, Pellicoro A, Vernon MA, Boulter L, Aucott RL, Ali A, Hartland SN, Snowdon VK, Cappon A, Gordon-Walker TT, Williams MJ, Dunbar DR, Manning JR, van Rooijen N, Fallowfield JA, Forbes SJ, Iredale JP. Ramachandran P, et al. Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):E3186-95. doi: 10.1073/pnas.1119964109. Epub 2012 Oct 24. Proc Natl Acad Sci U S A. 2012. PMID: 23100531 Free PMC article.
Sphingosine-1-Phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis.
King A, Houlihan DD, Kavanagh D, Haldar D, Luu N, Owen A, Suresh S, Than NN, Reynolds G, Penny J, Sumption H, Ramachandran P, Henderson NC, Kalia N, Frampton J, Adams DH, Newsome PN. King A, et al. Among authors: ramachandran p. Gastroenterology. 2017 Jul;153(1):233-248.e16. doi: 10.1053/j.gastro.2017.03.022. Epub 2017 Mar 28. Gastroenterology. 2017. PMID: 28363640 Free PMC article.
11Beta-hydroxysteroid dehydrogenase-1 deficiency or inhibition enhances hepatic myofibroblast activation in murine liver fibrosis.
Zou X, Ramachandran P, Kendall TJ, Pellicoro A, Dora E, Aucott RL, Manwani K, Man TY, Chapman KE, Henderson NC, Forbes SJ, Webster SP, Iredale JP, Walker BR, Michailidou Z. Zou X, et al. Among authors: ramachandran p. Hepatology. 2018 Jun;67(6):2167-2181. doi: 10.1002/hep.29734. Epub 2018 Feb 22. Hepatology. 2018. PMID: 29251794 Free PMC article.
Resolving the fibrotic niche of human liver cirrhosis at single-cell level.
Ramachandran P, Dobie R, Wilson-Kanamori JR, Dora EF, Henderson BEP, Luu NT, Portman JR, Matchett KP, Brice M, Marwick JA, Taylor RS, Efremova M, Vento-Tormo R, Carragher NO, Kendall TJ, Fallowfield JA, Harrison EM, Mole DJ, Wigmore SJ, Newsome PN, Weston CJ, Iredale JP, Tacke F, Pollard JW, Ponting CP, Marioni JC, Teichmann SA, Henderson NC. Ramachandran P, et al. Nature. 2019 Nov;575(7783):512-518. doi: 10.1038/s41586-019-1631-3. Epub 2019 Oct 9. Nature. 2019. PMID: 31597160 Free PMC article.
Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis.
Dobie R, Wilson-Kanamori JR, Henderson BEP, Smith JR, Matchett KP, Portman JR, Wallenborg K, Picelli S, Zagorska A, Pendem SV, Hudson TE, Wu MM, Budas GR, Breckenridge DG, Harrison EM, Mole DJ, Wigmore SJ, Ramachandran P, Ponting CP, Teichmann SA, Marioni JC, Henderson NC. Dobie R, et al. Among authors: ramachandran p. Cell Rep. 2019 Nov 12;29(7):1832-1847.e8. doi: 10.1016/j.celrep.2019.10.024. Cell Rep. 2019. PMID: 31722201 Free PMC article.
712 results