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Cutting Edge: Caspase-8 Is a Linchpin in Caspase-3 and Gasdermin D Activation to Control Cell Death, Cytokine Release, and Host Defense during Influenza A Virus Infection.
Wang Y, Karki R, Zheng M, Kancharana B, Lee S, Kesavardhana S, Hansen BS, Pruett-Miller SM, Kanneganti TD. Wang Y, et al. Among authors: kesavardhana s. J Immunol. 2021 Nov 15;207(10):2411-2416. doi: 10.4049/jimmunol.2100757. Epub 2021 Oct 18. J Immunol. 2021. PMID: 34663620 Free PMC article.
Caspases in Cell Death, Inflammation, and Pyroptosis.
Kesavardhana S, Malireddi RKS, Kanneganti TD. Kesavardhana S, et al. Annu Rev Immunol. 2020 Apr 26;38:567-595. doi: 10.1146/annurev-immunol-073119-095439. Epub 2020 Feb 4. Annu Rev Immunol. 2020. PMID: 32017655 Free PMC article. Review.
IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.
Man SM, Karki R, Sasai M, Place DE, Kesavardhana S, Temirov J, Frase S, Zhu Q, Malireddi RKS, Kuriakose T, Peters JL, Neale G, Brown SA, Yamamoto M, Kanneganti TD. Man SM, et al. Among authors: kesavardhana s. Cell. 2016 Oct 6;167(2):382-396.e17. doi: 10.1016/j.cell.2016.09.012. Epub 2016 Sep 29. Cell. 2016. PMID: 27693356 Free PMC article.
Stressed-out ROS take a silent death route.
Kesavardhana S, Kanneganti TD. Kesavardhana S, et al. Nat Immunol. 2018 Feb;19(2):103-105. doi: 10.1038/s41590-017-0034-6. Nat Immunol. 2018. PMID: 29348507 No abstract available.
DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome.
Samir P, Kesavardhana S, Patmore DM, Gingras S, Malireddi RKS, Karki R, Guy CS, Briard B, Place DE, Bhattacharya A, Sharma BR, Nourse A, King SV, Pitre A, Burton AR, Pelletier S, Gilbertson RJ, Kanneganti TD. Samir P, et al. Among authors: kesavardhana s. Nature. 2019 Sep;573(7775):590-594. doi: 10.1038/s41586-019-1551-2. Epub 2019 Sep 11. Nature. 2019. PMID: 31511697 Free PMC article.
29 results