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Knockdown of angiopoietin-like 2 induces clearance of vascular endothelial senescent cells by apoptosis, promotes endothelial repair and slows atherogenesis in mice.
Caland L, Labbé P, Mamarbachi M, Villeneuve L, Ferbeyre G, Noly PE, Carrier M, Thorin-Trescases N, Thorin É. Caland L, et al. Among authors: thorin e, thorin trescases n. Aging (Albany NY). 2019 Jun 11;11(11):3832-3850. doi: 10.18632/aging.102020. Aging (Albany NY). 2019. PMID: 31186381 Free PMC article.
Cellular senescence in endothelial cells from atherosclerotic patients is accelerated by oxidative stress associated with cardiovascular risk factors.
Voghel G, Thorin-Trescases N, Farhat N, Nguyen A, Villeneuve L, Mamarbachi AM, Fortier A, Perrault LP, Carrier M, Thorin E. Voghel G, et al. Among authors: thorin e, thorin trescases n. Mech Ageing Dev. 2007 Nov-Dec;128(11-12):662-71. doi: 10.1016/j.mad.2007.09.006. Epub 2007 Oct 13. Mech Ageing Dev. 2007. PMID: 18022214
Chronic treatment with N-acetyl-cystein delays cellular senescence in endothelial cells isolated from a subgroup of atherosclerotic patients.
Voghel G, Thorin-Trescases N, Farhat N, Mamarbachi AM, Villeneuve L, Fortier A, Perrault LP, Carrier M, Thorin E. Voghel G, et al. Among authors: thorin e, thorin trescases n. Mech Ageing Dev. 2008 May;129(5):261-70. doi: 10.1016/j.mad.2008.01.004. Epub 2008 Jan 20. Mech Ageing Dev. 2008. PMID: 18302967 Free PMC article.
Heart rate reduction by ivabradine reduces diastolic dysfunction and cardiac fibrosis.
Busseuil D, Shi Y, Mecteau M, Brand G, Gillis MA, Thorin E, Asselin C, Roméo P, Leung TK, Latour JG, Des Rosiers C, Bouly M, Rhéaume E, Tardif JC. Busseuil D, et al. Among authors: thorin e. Cardiology. 2010;117(3):234-42. doi: 10.1159/000322905. Epub 2011 Jan 8. Cardiology. 2010. PMID: 21212673 Free article.
175 results