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Validation of lipid-related therapeutic targets for coronary heart disease prevention using human genetics.
Gordillo-Marañón M, Zwierzyna M, Charoen P, Drenos F, Chopade S, Shah T, Engmann J, Chaturvedi N, Papacosta O, Wannamethee G, Wong A, Sofat R, Kivimaki M, Price JF, Hughes AD, Gaunt TR, Lawlor DA, Gaulton A, Hingorani AD, Schmidt AF, Finan C. Gordillo-Marañón M, et al. Among authors: kivimaki m. Nat Commun. 2021 Oct 21;12(1):6120. doi: 10.1038/s41467-021-25731-z. Nat Commun. 2021. PMID: 34675202 Free PMC article.
The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4,610 cases amongst 18,637 participants.
Lawlor DA, Harbord RM, Timpson NJ, Lowe GD, Rumley A, Gaunt TR, Baker I, Yarnell JW, Kivimäki M, Kumari M, Norman PE, Jamrozik K, Hankey GJ, Almeida OP, Flicker L, Warrington N, Marmot MG, Ben-Shlomo Y, Palmer LJ, Day IN, Ebrahim S, Smith GD. Lawlor DA, et al. Among authors: kivimaki m. PLoS One. 2008 Aug 20;3(8):e3011. doi: 10.1371/journal.pone.0003011. PLoS One. 2008. PMID: 18714384 Free PMC article.
Evaluating the causal relevance of diverse risk markers: horizontal systematic review.
Kuper H, Nicholson A, Kivimaki M, Aitsi-Selmi A, Cavalleri G, Deanfield JE, Heuschmann P, Jouven X, Malyutina S, Mayosi BM, Sans S, Thomsen T, Witteman JC, Hingorani AD, Lawlor DA, Hemingway H. Kuper H, et al. Among authors: kivimaki m. BMJ. 2009 Nov 5;339:b4265. doi: 10.1136/bmj.b4265. BMJ. 2009. PMID: 19892791 Free PMC article. Review.
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD; ASCOT investigators; NORDIL investigators; BRIGHT Consortium. Talmud PJ, et al. Among authors: kivimaki m. Am J Hum Genet. 2009 Nov;85(5):628-42. doi: 10.1016/j.ajhg.2009.10.014. Am J Hum Genet. 2009. PMID: 19913121 Free PMC article.
Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms.
Sofat R, Hingorani AD, Smeeth L, Humphries SE, Talmud PJ, Cooper J, Shah T, Sandhu MS, Ricketts SL, Boekholdt SM, Wareham N, Khaw KT, Kumari M, Kivimaki M, Marmot M, Asselbergs FW, van der Harst P, Dullaart RP, Navis G, van Veldhuisen DJ, Van Gilst WH, Thompson JF, McCaskie P, Palmer LJ, Arca M, Quagliarini F, Gaudio C, Cambien F, Nicaud V, Poirer O, Gudnason V, Isaacs A, Witteman JC, van Duijn CM, Pencina M, Vasan RS, D'Agostino RB Sr, Ordovas J, Li TY, Kakko S, Kauma H, Savolainen MJ, Kesäniemi YA, Sandhofer A, Paulweber B, Sorli JV, Goto A, Yokoyama S, Okumura K, Horne BD, Packard C, Freeman D, Ford I, Sattar N, McCormack V, Lawlor DA, Ebrahim S, Smith GD, Kastelein JJ, Deanfield J, Casas JP. Sofat R, et al. Among authors: kivimaki m. Circulation. 2010 Jan 5;121(1):52-62. doi: 10.1161/CIRCULATIONAHA.109.865444. Epub 2009 Dec 21. Circulation. 2010. PMID: 20026784 Free PMC article.
Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies.
Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration; Sarwar N, Sandhu MS, Ricketts SL, Butterworth AS, Di Angelantonio E, Boekholdt SM, Ouwehand W, Watkins H, Samani NJ, Saleheen D, Lawlor D, Reilly MP, Hingorani AD, Talmud PJ, Danesh J. Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration, et al. Lancet. 2010 May 8;375(9726):1634-9. doi: 10.1016/S0140-6736(10)60545-4. Lancet. 2010. PMID: 20452521 Free PMC article.
PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry.
Casas JP, Ninio E, Panayiotou A, Palmen J, Cooper JA, Ricketts SL, Sofat R, Nicolaides AN, Corsetti JP, Fowkes FG, Tzoulaki I, Kumari M, Brunner EJ, Kivimaki M, Marmot MG, Hoffmann MM, Winkler K, März W, Ye S, Stirnadel HA, Boekholdt SM, Khaw KT, Humphries SE, Sandhu MS, Hingorani AD, Talmud PJ. Casas JP, et al. Among authors: kivimaki m. Circulation. 2010 Jun 1;121(21):2284-93. doi: 10.1161/CIRCULATIONAHA.109.923383. Epub 2010 May 17. Circulation. 2010. PMID: 20479152 Free PMC article.
1,457 results