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Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2.
Chella Krishnan K, Vergnes L, Acín-Pérez R, Stiles L, Shum M, Ma L, Mouisel E, Pan C, Moore TM, Péterfy M, Romanoski CE, Reue K, Björkegren JLM, Laakso M, Liesa M, Lusis AJ. Chella Krishnan K, et al. Among authors: stiles l. Nat Metab. 2021 Nov;3(11):1552-1568. doi: 10.1038/s42255-021-00481-w. Epub 2021 Oct 25. Nat Metab. 2021. PMID: 34697471 Free PMC article.
Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis.
Mahdaviani K, Benador IY, Su S, Gharakhanian RA, Stiles L, Trudeau KM, Cardamone M, Enríquez-Zarralanga V, Ritou E, Aprahamian T, Oliveira MF, Corkey BE, Perissi V, Liesa M, Shirihai OS. Mahdaviani K, et al. Among authors: stiles l. EMBO Rep. 2017 Jul;18(7):1123-1138. doi: 10.15252/embr.201643827. Epub 2017 May 24. EMBO Rep. 2017. PMID: 28539390 Free PMC article.
Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis.
Divakaruni AS, Hsieh WY, Minarrieta L, Duong TN, Kim KKO, Desousa BR, Andreyev AY, Bowman CE, Caradonna K, Dranka BP, Ferrick DA, Liesa M, Stiles L, Rogers GW, Braas D, Ciaraldi TP, Wolfgang MJ, Sparwasser T, Berod L, Bensinger SJ, Murphy AN. Divakaruni AS, et al. Among authors: stiles l. Cell Metab. 2018 Sep 4;28(3):490-503.e7. doi: 10.1016/j.cmet.2018.06.001. Epub 2018 Jun 28. Cell Metab. 2018. PMID: 30043752 Free PMC article.
Mitochondrial Proton Leak Regulated by Cyclophilin D Elevates Insulin Secretion in Islets at Nonstimulatory Glucose Levels.
Taddeo EP, Alsabeeh N, Baghdasarian S, Wikstrom JD, Ritou E, Sereda S, Erion K, Li J, Stiles L, Abdulla M, Swanson Z, Wilhelm JJ, Bellin MD, Kibbey RG, Liesa M, Shirihai OS. Taddeo EP, et al. Among authors: stiles l. Diabetes. 2020 Feb;69(2):131-145. doi: 10.2337/db19-0379. Epub 2019 Nov 18. Diabetes. 2020. PMID: 31740442 Free PMC article.
Sex-specific metabolic functions of adipose Lipocalin-2.
Chella Krishnan K, Sabir S, Shum M, Meng Y, Acín-Pérez R, Lang JM, Floyd RR, Vergnes L, Seldin MM, Fuqua BK, Jayasekera DW, Nand SK, Anum DC, Pan C, Stiles L, Péterfy M, Reue K, Liesa M, Lusis AJ. Chella Krishnan K, et al. Among authors: stiles l. Mol Metab. 2019 Dec;30:30-47. doi: 10.1016/j.molmet.2019.09.009. Epub 2019 Sep 27. Mol Metab. 2019. PMID: 31767179 Free PMC article.
A novel approach to measure mitochondrial respiration in frozen biological samples.
Acin-Perez R, Benador IY, Petcherski A, Veliova M, Benavides GA, Lagarrigue S, Caudal A, Vergnes L, Murphy AN, Karamanlidis G, Tian R, Reue K, Wanagat J, Sacks H, Amati F, Darley-Usmar VM, Liesa M, Divakaruni AS, Stiles L, Shirihai OS. Acin-Perez R, et al. Among authors: stiles l. EMBO J. 2020 Jul 1;39(13):e104073. doi: 10.15252/embj.2019104073. Epub 2020 May 20. EMBO J. 2020. PMID: 32432379 Free PMC article.
Liver Pyruvate Kinase Promotes NAFLD/NASH in Both Mice and Humans in a Sex-Specific Manner.
Chella Krishnan K, Floyd RR, Sabir S, Jayasekera DW, Leon-Mimila PV, Jones AE, Cortez AA, Shravah V, Péterfy M, Stiles L, Canizales-Quinteros S, Divakaruni AS, Huertas-Vazquez A, Lusis AJ. Chella Krishnan K, et al. Among authors: stiles l. Cell Mol Gastroenterol Hepatol. 2021;11(2):389-406. doi: 10.1016/j.jcmgh.2020.09.004. Epub 2020 Sep 14. Cell Mol Gastroenterol Hepatol. 2021. PMID: 32942044 Free PMC article.
Age-induced mitochondrial DNA point mutations are inadequate to alter metabolic homeostasis in response to nutrient challenge.
Moore TM, Zhou Z, Strumwasser AR, Cohn W, Lin AJ, Cory K, Whitney K, Ho T, Ho T, Lee JL, Rucker DH, Hoang AN, Widjaja K, Abrishami AD, Charugundla S, Stiles L, Whitelegge JP, Turcotte LP, Wanagat J, Hevener AL. Moore TM, et al. Among authors: stiles l. Aging Cell. 2020 Nov;19(11):e13166. doi: 10.1111/acel.13166. Epub 2020 Oct 13. Aging Cell. 2020. PMID: 33049094 Free PMC article.
107 results