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Ontogeny and function of the circadian clock in intestinal organoids.
Rosselot AE, Park M, Kim M, Matsu-Ura T, Wu G, Flores DE, Subramanian KR, Lee S, Sundaram N, Broda TR, McCauley HA, Hawkins JA, Chetal K, Salomonis N, Shroyer NF, Helmrath MA, Wells JM, Hogenesch JB, Moore SR, Hong CI. Rosselot AE, et al. Among authors: broda tr. EMBO J. 2022 Dec 17;41(2):e106973. doi: 10.15252/embj.2020106973. Epub 2021 Oct 27. EMBO J. 2022. PMID: 34704277 Free PMC article.
Aggregation of cryopreserved mid-hindgut endoderm for more reliable and reproducible hPSC-derived small intestinal organoid generation.
Pitstick AL, Poling HM, Sundaram N, Lewis PL, Kechele DO, Sanchez JG, Scott MA, Broda TR, Helmrath MA, Wells JM, Mayhew CN. Pitstick AL, et al. Among authors: broda tr. Stem Cell Reports. 2022 Aug 9;17(8):1889-1902. doi: 10.1016/j.stemcr.2022.06.011. Epub 2022 Jul 28. Stem Cell Reports. 2022. PMID: 35905739 Free PMC article.
Intestinal organoids: roadmap to the clinic.
Kasendra M, Troutt M, Broda T, Bacon WC, Wang TC, Niland JC, Helmrath MA. Kasendra M, et al. Am J Physiol Gastrointest Liver Physiol. 2021 Jul 1;321(1):G1-G10. doi: 10.1152/ajpgi.00425.2020. Epub 2021 May 5. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 33950707 Free PMC article. Review.
Using Human Induced Pluripotent Stem Cell-Derived Organoids to Identify New Pathologies in Patients With PDX1 Mutations.
Krishnamurthy M, Kechele DO, Broda T, Zhang X, Enriquez JR, McCauley HA, Sanchez JG, McCracken K, Palermo J, Bernieh A, Collins MH, Thomas IH, Neef HC, Heider A, Dauber A, Wells JM. Krishnamurthy M, et al. Gastroenterology. 2022 Oct;163(4):1053-1063.e7. doi: 10.1053/j.gastro.2022.06.083. Epub 2022 Jul 6. Gastroenterology. 2022. PMID: 35803312 Free PMC article.
Wnt/β-catenin promotes gastric fundus specification in mice and humans.
McCracken KW, Aihara E, Martin B, Crawford CM, Broda T, Treguier J, Zhang X, Shannon JM, Montrose MH, Wells JM. McCracken KW, et al. Nature. 2017 Jan 12;541(7636):182-187. doi: 10.1038/nature21021. Epub 2017 Jan 4. Nature. 2017. PMID: 28052057 Free PMC article.