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Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L.
J Med Chem. 2022 Feb 24;65(4):2956-2970. doi: 10.1021/acs.jmedchem.1c01494. Epub 2021 Nov 3.
J Med Chem. 2022.
PMID: 34730959
Free PMC article.
Antiviral cyclic peptides targeting the main protease of SARS-CoV-2.
Johansen-Leete J, Ullrich S, Fry SE, Frkic R, Bedding MJ, Aggarwal A, Ashhurst AS, Ekanayake KB, Mahawaththa MC, Sasi VM, Luedtke S, Ford DJ, O'Donoghue AJ, Passioura T, Larance M, Otting G, Turville S, Jackson CJ, Nitsche C, Payne RJ.
Johansen-Leete J, et al. Among authors: bedding mj.
Chem Sci. 2022 Feb 28;13(13):3826-3836. doi: 10.1039/d1sc06750h. eCollection 2022 Mar 30.
Chem Sci. 2022.
PMID: 35432913
Free PMC article.
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Diselenide-selenoester ligation in the chemical synthesis of proteins.
Bedding MJ, Kulkarni SS, Payne RJ.
Bedding MJ, et al.
Methods Enzymol. 2022;662:363-399. doi: 10.1016/bs.mie.2021.10.017. Epub 2021 Dec 7.
Methods Enzymol. 2022.
PMID: 35101218
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Late-stage modification of peptides and proteins at cysteine with diaryliodonium salts.
Byrne SA, Bedding MJ, Corcilius L, Ford DJ, Zhong Y, Franck C, Larance M, Mackay JP, Payne RJ.
Byrne SA, et al. Among authors: bedding mj.
Chem Sci. 2021 Sep 30;12(42):14159-14166. doi: 10.1039/d1sc03127a. eCollection 2021 Nov 3.
Chem Sci. 2021.
PMID: 34760200
Free PMC article.
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Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity.
Bedding MJ, Franck C, Johansen-Leete J, Aggarwal A, Maxwell JWC, Patel K, Hawkins PME, Low JKK, Siddiquee R, Sani HM, Ford DJ, Turville S, Mackay JP, Passioura T, Christie M, Payne RJ.
Bedding MJ, et al.
ACS Chem Biol. 2024 Jan 19;19(1):141-152. doi: 10.1021/acschembio.3c00568. Epub 2023 Dec 12.
ACS Chem Biol. 2024.
PMID: 38085789
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Electrochemical Modification of Polypeptides at Selenocysteine.
Mackay AS, Maxwell JWC, Bedding MJ, Kulkarni SS, Byrne SA, Kambanis L, Popescu MV, Paton RS, Malins LR, Ashhurst AS, Corcilius L, Payne RJ.
Mackay AS, et al. Among authors: bedding mj.
Angew Chem Int Ed Engl. 2023 Dec 11;62(50):e202313037. doi: 10.1002/anie.202313037. Epub 2023 Nov 9.
Angew Chem Int Ed Engl. 2023.
PMID: 37818778
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