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Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L.
Ashhurst AS, Tang AH, Fajtová P, Yoon MC, Aggarwal A, Bedding MJ, Stoye A, Beretta L, Pwee D, Drelich A, Skinner D, Li L, Meek TD, McKerrow JH, Hook V, Tseng CT, Larance M, Turville S, Gerwick WH, O'Donoghue AJ, Payne RJ. Ashhurst AS, et al. Among authors: larance m. J Med Chem. 2022 Feb 24;65(4):2956-2970. doi: 10.1021/acs.jmedchem.1c01494. Epub 2021 Nov 3. J Med Chem. 2022. PMID: 34730959 Free PMC article.
Native Size-Exclusion Chromatography-Based Mass Spectrometry Reveals New Components of the Early Heat Shock Protein 90 Inhibition Response Among Limited Global Changes.
Samant RS, Batista S, Larance M, Ozer B, Milton CI, Bludau I, Wu E, Biggins L, Andrews S, Hervieu A, Johnston HE, Al-Lazikhani B, Lamond AI, Clarke PA, Workman P. Samant RS, et al. Among authors: larance m. Mol Cell Proteomics. 2023 Feb;22(2):100485. doi: 10.1016/j.mcpro.2022.100485. Epub 2022 Dec 20. Mol Cell Proteomics. 2023. PMID: 36549590 Free PMC article.
Overexpression of VIRMA confers vulnerability to breast cancers via the m6A-dependent regulation of unfolded protein response.
Lee Q, Song R, Phan DAV, Pinello N, Tieng J, Su A, Halstead JM, Wong ACH, van Geldermalsen M, Lee BS, Rong B, Cook KM, Larance M, Liu R, Lan F, Tiffen JC, Wong JJ. Lee Q, et al. Among authors: larance m. Cell Mol Life Sci. 2023 May 19;80(6):157. doi: 10.1007/s00018-023-04799-4. Cell Mol Life Sci. 2023. PMID: 37208522 Free PMC article.
Endoplasmic reticulum protein 5 attenuates platelet endoplasmic reticulum stress and secretion in a mouse model.
Lay AJ, Dupuy A, Hagimola L, Tieng J, Larance M, Zhang Y, Yang J, Kong Y, Chiu J, Gray E, Qin Z, Schmidt D, Maclean J, Hofma B, Ellis M, Kalev-Zylinska M, Argon Y, Jackson SP, Hogg P, Passam FH. Lay AJ, et al. Among authors: larance m. Blood Adv. 2023 May 9;7(9):1650-1665. doi: 10.1182/bloodadvances.2022008457. Blood Adv. 2023. PMID: 36508284 Free PMC article.
Semisynthesis of an evasin from tick saliva reveals a critical role of tyrosine sulfation for chemokine binding and inhibition.
Franck C, Foster SR, Johansen-Leete J, Chowdhury S, Cielesh M, Bhusal RP, Mackay JP, Larance M, Stone MJ, Payne RJ. Franck C, et al. Among authors: larance m. Proc Natl Acad Sci U S A. 2020 Jun 9;117(23):12657-12664. doi: 10.1073/pnas.2000605117. Epub 2020 May 27. Proc Natl Acad Sci U S A. 2020. PMID: 32461364 Free PMC article.
Total Synthesis of Glycosylated Human Interferon-γ.
Wang X, Ashhurst AS, Dowman LJ, Watson EE, Li HY, Fairbanks AJ, Larance M, Kwan A, Payne RJ. Wang X, et al. Among authors: larance m. Org Lett. 2020 Sep 4;22(17):6863-6867. doi: 10.1021/acs.orglett.0c02401. Epub 2020 Aug 24. Org Lett. 2020. PMID: 32830985
Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L.
Ashhurst AS, Tang AH, Fajtová P, Yoon M, Aggarwal A, Stoye A, Larance M, Beretta L, Drelich A, Skinner D, Li L, Meek TD, McKerrow JH, Hook V, Tseng CK, Turville S, Gerwick WH, O'Donoghue AJ, Payne RJ. Ashhurst AS, et al. Among authors: larance m. bioRxiv [Preprint]. 2020 Dec 24:2020.12.23.424111. doi: 10.1101/2020.12.23.424111. bioRxiv. 2020. PMID: 33398273 Free PMC article. Updated. Preprint.
74 results