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Randomized Controlled-Feeding Study of Dietary Emulsifier Carboxymethylcellulose Reveals Detrimental Impacts on the Gut Microbiota and Metabolome.
Chassaing B, Compher C, Bonhomme B, Liu Q, Tian Y, Walters W, Nessel L, Delaroque C, Hao F, Gershuni V, Chau L, Ni J, Bewtra M, Albenberg L, Bretin A, McKeever L, Ley RE, Patterson AD, Wu GD, Gewirtz AT, Lewis JD. Chassaing B, et al. Among authors: chau l. Gastroenterology. 2022 Mar;162(3):743-756. doi: 10.1053/j.gastro.2021.11.006. Epub 2021 Nov 11. Gastroenterology. 2022. PMID: 34774538 Free PMC article. Clinical Trial.
Dendritic cell expression of the signaling molecule TRAF6 is critical for gut microbiota-dependent immune tolerance.
Han D, Walsh MC, Cejas PJ, Dang NN, Kim YF, Kim J, Charrier-Hisamuddin L, Chau L, Zhang Q, Bittinger K, Bushman FD, Turka LA, Shen H, Reizis B, Defranco AL, Wu GD, Choi Y. Han D, et al. Among authors: chau l. Immunity. 2013 Jun 27;38(6):1211-22. doi: 10.1016/j.immuni.2013.05.012. Epub 2013 Jun 20. Immunity. 2013. PMID: 23791643 Free PMC article.
Engineering the gut microbiota to treat hyperammonemia.
Shen TC, Albenberg L, Bittinger K, Chehoud C, Chen YY, Judge CA, Chau L, Ni J, Sheng M, Lin A, Wilkins BJ, Buza EL, Lewis JD, Daikhin Y, Nissim I, Yudkoff M, Bushman FD, Wu GD. Shen TC, et al. Among authors: chau l. J Clin Invest. 2015 Jul 1;125(7):2841-50. doi: 10.1172/JCI79214. Epub 2015 Jun 22. J Clin Invest. 2015. PMID: 26098218 Free PMC article.
A role for bacterial urease in gut dysbiosis and Crohn's disease.
Ni J, Shen TD, Chen EZ, Bittinger K, Bailey A, Roggiani M, Sirota-Madi A, Friedman ES, Chau L, Lin A, Nissim I, Scott J, Lauder A, Hoffmann C, Rivas G, Albenberg L, Baldassano RN, Braun J, Xavier RJ, Clish CB, Yudkoff M, Li H, Goulian M, Bushman FD, Lewis JD, Wu GD. Ni J, et al. Among authors: chau l. Sci Transl Med. 2017 Nov 15;9(416):eaah6888. doi: 10.1126/scitranslmed.aah6888. Sci Transl Med. 2017. PMID: 29141885 Free PMC article.
Microbes vs. chemistry in the origin of the anaerobic gut lumen.
Friedman ES, Bittinger K, Esipova TV, Hou L, Chau L, Jiang J, Mesaros C, Lund PJ, Liang X, FitzGerald GA, Goulian M, Lee D, Garcia BA, Blair IA, Vinogradov SA, Wu GD. Friedman ES, et al. Among authors: chau l. Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4170-4175. doi: 10.1073/pnas.1718635115. Epub 2018 Apr 2. Proc Natl Acad Sci U S A. 2018. PMID: 29610310 Free PMC article.
FXR-Dependent Modulation of the Human Small Intestinal Microbiome by the Bile Acid Derivative Obeticholic Acid.
Friedman ES, Li Y, Shen TD, Jiang J, Chau L, Adorini L, Babakhani F, Edwards J, Shapiro D, Zhao C, Carr RM, Bittinger K, Li H, Wu GD. Friedman ES, et al. Among authors: chau l. Gastroenterology. 2018 Dec;155(6):1741-1752.e5. doi: 10.1053/j.gastro.2018.08.022. Epub 2018 Aug 23. Gastroenterology. 2018. PMID: 30144429 Free PMC article. Clinical Trial.
Mitochondrial dysfunction in inflammatory bowel disease alters intestinal epithelial metabolism of hepatic acylcarnitines.
Smith SA, Ogawa SA, Chau L, Whelan KA, Hamilton KE, Chen J, Tan L, Chen EZ, Keilbaugh S, Fogt F, Bewtra M, Braun J, Xavier RJ, Clish CB, Slaff B, Weljie AM, Bushman FD, Lewis JD, Li H, Master SR, Bennett MJ, Nakagawa H, Wu GD. Smith SA, et al. Among authors: chau l. J Clin Invest. 2021 Jan 4;131(1):e133371. doi: 10.1172/JCI133371. J Clin Invest. 2021. PMID: 33141762 Free PMC article.
Role of dietary fiber in the recovery of the human gut microbiome and its metabolome.
Tanes C, Bittinger K, Gao Y, Friedman ES, Nessel L, Paladhi UR, Chau L, Panfen E, Fischbach MA, Braun J, Xavier RJ, Clish CB, Li H, Bushman FD, Lewis JD, Wu GD. Tanes C, et al. Among authors: chau l. Cell Host Microbe. 2021 Mar 10;29(3):394-407.e5. doi: 10.1016/j.chom.2020.12.012. Epub 2021 Jan 12. Cell Host Microbe. 2021. PMID: 33440171 Free PMC article.
345 results