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Pluripotent stem cell differentiation reveals distinct developmental pathways regulating lung- versus thyroid-lineage specification.
Serra M, Alysandratos KD, Hawkins F, McCauley KB, Jacob A, Choi J, Caballero IS, Vedaie M, Kurmann AA, Ikonomou L, Hollenberg AN, Shannon JM, Kotton DN. Serra M, et al. Among authors: kotton dn. Development. 2017 Nov 1;144(21):3879-3893. doi: 10.1242/dev.150193. Epub 2017 Sep 25. Development. 2017. PMID: 28947536 Free PMC article.
Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium.
McCauley KB, Alysandratos KD, Jacob A, Hawkins F, Caballero IS, Vedaie M, Yang W, Slovik KJ, Morley M, Carraro G, Kook S, Guttentag SH, Stripp BR, Morrisey EE, Kotton DN. McCauley KB, et al. Among authors: kotton dn. Stem Cell Reports. 2018 May 8;10(5):1579-1595. doi: 10.1016/j.stemcr.2018.03.013. Epub 2018 Apr 12. Stem Cell Reports. 2018. PMID: 29657097 Free PMC article.
The in vivo genetic program of murine primordial lung epithelial progenitors.
Ikonomou L, Herriges MJ, Lewandowski SL, Marsland R 3rd, Villacorta-Martin C, Caballero IS, Frank DB, Sanghrajka RM, Dame K, Kańduła MM, Hicks-Berthet J, Lawton ML, Christodoulou C, Fabian AJ, Kolaczyk E, Varelas X, Morrisey EE, Shannon JM, Mehta P, Kotton DN. Ikonomou L, et al. Among authors: kotton dn. Nat Commun. 2020 Jan 31;11(1):635. doi: 10.1038/s41467-020-14348-3. Nat Commun. 2020. PMID: 32005814 Free PMC article.
Epithelial Stem and Progenitor Cells in Lung Repair and Regeneration.
Alysandratos KD, Herriges MJ, Kotton DN. Alysandratos KD, et al. Among authors: kotton dn. Annu Rev Physiol. 2021 Feb 10;83:529-550. doi: 10.1146/annurev-physiol-041520-092904. Epub 2020 Oct 19. Annu Rev Physiol. 2021. PMID: 33074772 Free PMC article. Review.
Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease.
Alysandratos KD, Russo SJ, Petcherski A, Taddeo EP, Acín-Pérez R, Villacorta-Martin C, Jean JC, Mulugeta S, Rodriguez LR, Blum BC, Hekman RM, Hix OT, Minakin K, Vedaie M, Kook S, Tilston-Lunel AM, Varelas X, Wambach JA, Cole FS, Hamvas A, Young LR, Liesa M, Emili A, Guttentag SH, Shirihai OS, Beers MF, Kotton DN. Alysandratos KD, et al. Among authors: kotton dn. Cell Rep. 2021 Aug 31;36(9):109636. doi: 10.1016/j.celrep.2021.109636. Cell Rep. 2021. PMID: 34469722 Free PMC article.
Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell-derived alveolar epithelium.
Abo KM, Sainz de Aja J, Lindstrom-Vautrin J, Alysandratos KD, Richards A, Garcia-de-Alba C, Huang J, Hix OT, Werder RB, Bullitt E, Hinds A, Falconer I, Villacorta-Martin C, Jaenisch R, Kim CF, Kotton DN, Wilson AA. Abo KM, et al. Among authors: kotton dn. JCI Insight. 2022 Mar 22;7(6):e155589. doi: 10.1172/jci.insight.155589. JCI Insight. 2022. PMID: 35315362 Free PMC article.
162 results