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Predicting clinical response to anticancer drugs using an ex vivo platform that captures tumour heterogeneity.
Majumder B, Baraneedharan U, Thiyagarajan S, Radhakrishnan P, Narasimhan H, Dhandapani M, Brijwani N, Pinto DD, Prasath A, Shanthappa BU, Thayakumar A, Surendran R, Babu GK, Shenoy AM, Kuriakose MA, Bergthold G, Horowitz P, Loda M, Beroukhim R, Agarwal S, Sengupta S, Sundaram M, Majumder PK. Majumder B, et al. Among authors: majumder pk. Nat Commun. 2015 Feb 27;6:6169. doi: 10.1038/ncomms7169. Nat Commun. 2015. PMID: 25721094 Free PMC article.
Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma.
Plentz R, Park JS, Rhim AD, Abravanel D, Hezel AF, Sharma SV, Gurumurthy S, Deshpande V, Kenific C, Settleman J, Majumder PK, Stanger BZ, Bardeesy N. Plentz R, et al. Among authors: majumder pk. Gastroenterology. 2009 May;136(5):1741-9.e6. doi: 10.1053/j.gastro.2009.01.008. Epub 2009 Jan 14. Gastroenterology. 2009. PMID: 19208345 Free PMC article.
Integrating Systems Biology and an Ex Vivo Human Tumor Model Elucidates PD-1 Blockade Response Dynamics.
Smalley M, Przedborski M, Thiyagarajan S, Pellowe M, Verma A, Brijwani N, Datta D, Jain M, Shanthappa BU, Kapoor V, Gopinath KS, Doval DC, Sabitha KS, Taroncher-Oldenburg G, Majumder B, Majumder P, Kohandel M, Goldman A. Smalley M, et al. iScience. 2020 Jun 26;23(6):101229. doi: 10.1016/j.isci.2020.101229. Epub 2020 Jun 2. iScience. 2020. PMID: 32554190 Free PMC article.
A prostatic intraepithelial neoplasia-dependent p27 Kip1 checkpoint induces senescence and inhibits cell proliferation and cancer progression.
Majumder PK, Grisanzio C, O'Connell F, Barry M, Brito JM, Xu Q, Guney I, Berger R, Herman P, Bikoff R, Fedele G, Baek WK, Wang S, Ellwood-Yen K, Wu H, Sawyers CL, Signoretti S, Hahn WC, Loda M, Sellers WR. Majumder PK, et al. Cancer Cell. 2008 Aug 12;14(2):146-55. doi: 10.1016/j.ccr.2008.06.002. Cancer Cell. 2008. PMID: 18691549 Free PMC article.
JAK-STAT inhibitor as a potential therapeutic opportunity in AML patients resistant to cytarabine and epigenetic therapy.
Babu G, Chaudhuri P, Rajappa M, Biswas M, Sansar B, Rajegowda C, Radhakrishnan A, Advani J, Tewary B, Radhakrishnan P, Thiyagarajan S, Chatterjee A, Upadhayaya RS, Majumder PK. Babu G, et al. Among authors: majumder pk. Cancer Biol Ther. 2021 Jan 2;22(1):66-78. doi: 10.1080/15384047.2020.1831371. Epub 2020 Dec 27. Cancer Biol Ther. 2021. PMID: 33356802 Free PMC article.
70 results