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Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant complex traits.
Pahl MC, Doege CA, Hodge KM, Littleton SH, Leonard ME, Lu S, Rausch R, Pippin JA, De Rosa MC, Basak A, Bradfield JP, Hammond RK, Boehm K, Berkowitz RI, Lasconi C, Su C, Chesi A, Johnson ME, Wells AD, Voight BF, Leibel RL, Cousminer DL, Grant SFA. Pahl MC, et al. Among authors: leibel rl. Nat Commun. 2021 Nov 19;12(1):6749. doi: 10.1038/s41467-021-27001-4. Nat Commun. 2021. PMID: 34799566 Free PMC article.
Human oocytes reprogram somatic cells to a pluripotent state.
Noggle S, Fung HL, Gore A, Martinez H, Satriani KC, Prosser R, Oum K, Paull D, Druckenmiller S, Freeby M, Greenberg E, Zhang K, Goland R, Sauer MV, Leibel RL, Egli D. Noggle S, et al. Among authors: leibel rl. Nature. 2011 Oct 5;478(7367):70-5. doi: 10.1038/nature10397. Nature. 2011. PMID: 21979046
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.
Kilpeläinen TO, Carli JF, Skowronski AA, Sun Q, Kriebel J, Feitosa MF, Hedman ÅK, Drong AW, Hayes JE, Zhao J, Pers TH, Schick U, Grarup N, Kutalik Z, Trompet S, Mangino M, Kristiansson K, Beekman M, Lyytikäinen LP, Eriksson J, Henneman P, Lahti J, Tanaka T, Luan J, Del Greco M F, Pasko D, Renström F, Willems SM, Mahajan A, Rose LM, Guo X, Liu Y, Kleber ME, Pérusse L, Gaunt T, Ahluwalia TS, Ju Sung Y, Ramos YF, Amin N, Amuzu A, Barroso I, Bellis C, Blangero J, Buckley BM, Böhringer S, I Chen YD, de Craen AJ, Crosslin DR, Dale CE, Dastani Z, Day FR, Deelen J, Delgado GE, Demirkan A, Finucane FM, Ford I, Garcia ME, Gieger C, Gustafsson S, Hallmans G, Hankinson SE, Havulinna AS, Herder C, Hernandez D, Hicks AA, Hunter DJ, Illig T, Ingelsson E, Ioan-Facsinay A, Jansson JO, Jenny NS, Jørgensen ME, Jørgensen T, Karlsson M, Koenig W, Kraft P, Kwekkeboom J, Laatikainen T, Ladwig KH, LeDuc CA, Lowe G, Lu Y, Marques-Vidal P, Meisinger C, Menni C, Morris AP, Myers RH, Männistö S, Nalls MA, Paternoster L, Peters A, Pradhan AD, Rankinen T, Rasmussen-Torvik LJ, Rathmann W, Rice TK, Brent Richards J, Ridker PM, Sattar N, Savage DB, Söderberg S, Timpson NJ, Vandenput L, van Heemst D, Uh HW, Vohl M… See abstract for full author list ➔ Kilpeläinen TO, et al. Among authors: leibel rl. Nat Commun. 2016 Feb 1;7:10494. doi: 10.1038/ncomms10494. Nat Commun. 2016. PMID: 26833098 Free PMC article.
Determination of the half-life of circulating leptin in the mouse.
Burnett LC, Skowronski AA, Rausch R, LeDuc CA, Leibel RL. Burnett LC, et al. Among authors: leibel rl. Int J Obes (Lond). 2017 Mar;41(3):355-359. doi: 10.1038/ijo.2016.238. Epub 2016 Dec 27. Int J Obes (Lond). 2017. PMID: 28025576 Free PMC article.
MC4R-dependent suppression of appetite by bone-derived lipocalin 2.
Mosialou I, Shikhel S, Liu JM, Maurizi A, Luo N, He Z, Huang Y, Zong H, Friedman RA, Barasch J, Lanzano P, Deng L, Leibel RL, Rubin M, Nickolas T, Chung W, Zeltser LM, Williams KW, Pessin JE, Kousteni S. Mosialou I, et al. Among authors: leibel rl. Nature. 2017 Mar 16;543(7645):385-390. doi: 10.1038/nature21697. Epub 2017 Mar 8. Nature. 2017. PMID: 28273060 Free PMC article.
ILDR2 has a negligible role in hepatic steatosis.
Millings EJ, De Rosa MC, Fleet S, Watanabe K, Rausch R, Egli D, Li G, Leduc CA, Zhang Y, Fischer SG, Leibel RL. Millings EJ, et al. Among authors: leibel rl. PLoS One. 2018 May 30;13(5):e0197548. doi: 10.1371/journal.pone.0197548. eCollection 2018. PLoS One. 2018. PMID: 29847571 Free PMC article.
340 results