Wells AD - Search Results

1

Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant complex traits.

Pahl MC, Doege CA, Hodge KM, Littleton SH, Leonard ME, Lu S, Rausch R, Pippin JA, De Rosa MC, Basak A, Bradfield JP, Hammond RK, Boehm K, Berkowitz RI, Lasconi C, Su C, Chesi A, Johnson ME, Wells AD, Voight BF, Leibel RL, Cousminer DL, Grant SFA. Pahl MC, et al. Among authors: wells ad. Nat Commun. 2021 Nov 19;12(1):6749. doi: 10.1038/s41467-021-27001-4. Nat Commun. 2021. PMID: 34799566 Free PMC article.

2

A ChIP-seq-defined genome-wide map of MEF2C binding reveals inflammatory pathways associated with its role in bone density determination.

Johnson ME, Deliard S, Zhu F, Xia Q, Wells AD, Hankenson KD, Grant SF. Johnson ME, et al. Among authors: wells ad. Calcif Tissue Int. 2014 Apr;94(4):396-402. doi: 10.1007/s00223-013-9824-5. Epub 2013 Dec 15. Calcif Tissue Int. 2014. PMID: 24337390

3

Genome-wide analyses of ChIP-Seq derived FOXA2 DNA occupancy in liver points to genetic networks underpinning multiple complex traits.

Johnson ME, Schug J, Wells AD, Kaestner KH, Grant SF. Johnson ME, et al. Among authors: wells ad. J Clin Endocrinol Metab. 2014 Aug;99(8):E1580-5. doi: 10.1210/jc.2013-4503. Epub 2014 May 30. J Clin Endocrinol Metab. 2014. PMID: 24878043 Free PMC article.

4

Two novel type 2 diabetes loci revealed through integration of TCF7L2 DNA occupancy and SNP association data.

Johnson ME, Zhao J, Schug J, Deliard S, Xia Q, Guy VC, Sainz J, Kaestner KH, Wells AD, Grant SF. Johnson ME, et al. Among authors: wells ad. BMJ Open Diabetes Res Care. 2014 Dec 1;2(1):e000052. doi: 10.1136/bmjdrc-2014-000052. eCollection 2014. BMJ Open Diabetes Res Care. 2014. PMID: 25469308 Free PMC article.

5

DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions.

Chen Y, Chen C, Zhang Z, Liu CC, Johnson ME, Espinoza CA, Edsall LE, Ren B, Zhou XJ, Grant SF, Wells AD, Chen L. Chen Y, et al. Among authors: wells ad. Nucleic Acids Res. 2015 Jan;43(2):1268-82. doi: 10.1093/nar/gku1373. Epub 2015 Jan 7. Nucleic Acids Res. 2015. PMID: 25567984 Free PMC article.

6

The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the expression of ACSL5.

Xia Q, Chesi A, Manduchi E, Johnston BT, Lu S, Leonard ME, Parlin UW, Rappaport EF, Huang P, Wells AD, Blobel GA, Johnson ME, Grant SFA. Xia Q, et al. Among authors: wells ad. Diabetologia. 2016 Nov;59(11):2360-2368. doi: 10.1007/s00125-016-4077-2. Epub 2016 Aug 18. Diabetologia. 2016. PMID: 27539148

7

Ndfip1 restricts mTORC1 signalling and glycolysis in regulatory T cells to prevent autoinflammatory disease.

Layman AAK, Deng G, O'Leary CE, Tadros S, Thomas RM, Dybas JM, Moser EK, Wells AD, Doliba NM, Oliver PM. Layman AAK, et al. Among authors: wells ad. Nat Commun. 2017 Jun 5;8:15677. doi: 10.1038/ncomms15677. Nat Commun. 2017. PMID: 28580955 Free PMC article.

8

A Dementia-Associated Risk Variant near TMEM106B Alters Chromatin Architecture and Gene Expression.

Gallagher MD, Posavi M, Huang P, Unger TL, Berlyand Y, Gruenewald AL, Chesi A, Manduchi E, Wells AD, Grant SFA, Blobel GA, Brown CD, Chen-Plotkin AS. Gallagher MD, et al. Among authors: wells ad. Am J Hum Genet. 2017 Nov 2;101(5):643-663. doi: 10.1016/j.ajhg.2017.09.004. Epub 2017 Oct 19. Am J Hum Genet. 2017. PMID: 29056226 Free PMC article.

9

The Loss of TET2 Promotes CD8⁺ T Cell Memory Differentiation.

Carty SA, Gohil M, Banks LB, Cotton RM, Johnson ME, Stelekati E, Wells AD, Wherry EJ, Koretzky GA, Jordan MS. Carty SA, et al. Among authors: wells ad. J Immunol. 2018 Jan 1;200(1):82-91. doi: 10.4049/jimmunol.1700559. Epub 2017 Nov 17. J Immunol. 2018. PMID: 29150566 Free PMC article.

10

Leveraging epigenomics and contactomics data to investigate SNP pairs in GWAS.

Manduchi E, Williams SM, Chesi A, Johnson ME, Wells AD, Grant SFA, Moore JH. Manduchi E, et al. Among authors: wells ad. Hum Genet. 2018 May;137(5):413-425. doi: 10.1007/s00439-018-1893-0. Epub 2018 May 24. Hum Genet. 2018. PMID: 29797095 Free PMC article.

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