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Tissue distribution and transcriptional regulation of CCN5 in the heart after myocardial infarction.
J Cell Commun Signal. 2022 Sep;16(3):377-395. doi: 10.1007/s12079-021-00659-7. Epub 2021 Dec 1.
J Cell Commun Signal. 2022.
PMID: 34854055
Free PMC article.
Connective tissue growth factor/CCN2 attenuates β-adrenergic receptor responsiveness and cardiotoxicity by induction of G protein-coupled receptor kinase-5 in cardiomyocytes.
Gravning J, Ahmed MS, Qvigstad E, Krobert K, Edvardsen T, Moe IT, Hagelin EM, Sagave J, Valen G, Levy FO, Osnes JB, Skomedal T, Attramadal H.
Gravning J, et al.
Mol Pharmacol. 2013 Sep;84(3):372-83. doi: 10.1124/mol.113.087312. Epub 2013 Jun 18.
Mol Pharmacol. 2013.
PMID: 23778361
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The carboxyl-terminal TSP1-homology domain is the biologically active effector peptide of matricellular protein CCN5 that counteracts profibrotic CCN2.
Zolfaghari S, Kaasbøll OJ, Monsen VT, Sredic B, Hagelin EMV, Attramadal H.
Zolfaghari S, et al. Among authors: hagelin emv.
J Biol Chem. 2023 Jan;299(1):102803. doi: 10.1016/j.jbc.2022.102803. Epub 2022 Dec 15.
J Biol Chem. 2023.
PMID: 36529291
Free PMC article.
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Connective tissue growth factor (CCN2) is a matricellular preproprotein controlled by proteolytic activation.
Kaasbøll OJ, Gadicherla AK, Wang JH, Monsen VT, Hagelin EMV, Dong MQ, Attramadal H.
Kaasbøll OJ, et al. Among authors: hagelin emv.
J Biol Chem. 2018 Nov 16;293(46):17953-17970. doi: 10.1074/jbc.RA118.004559. Epub 2018 Sep 27.
J Biol Chem. 2018.
PMID: 30262666
Free PMC article.
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CTGF/CCN2 Postconditioning Increases Tolerance of Murine Hearts towards Ischemia-Reperfusion Injury.
Kaasbøll OJ, Moe IT, Ahmed MS, Stang E, Hagelin EM, Attramadal H.
Kaasbøll OJ, et al.
PLoS One. 2016 Feb 12;11(2):e0149000. doi: 10.1371/journal.pone.0149000. eCollection 2016.
PLoS One. 2016.
PMID: 26872261
Free PMC article.
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CCN2 exerts direct cytoprotective actions in adult cardiac myocytes by activation of the PI3-kinase/Akt/GSK-3β signaling pathway.
Moe IT, Pham TA, Hagelin EM, Ahmed MS, Attramadal H.
Moe IT, et al.
J Cell Commun Signal. 2013 Mar;7(1):31-47. doi: 10.1007/s12079-012-0183-1. Epub 2012 Dec 4.
J Cell Commun Signal. 2013.
PMID: 23208610
Free PMC article.
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Adrenomedullin is increased in alveolar macrophages and released from the lungs into the circulation in severe heart failure.
Øie E, Ahmed MS, Ueland T, Sikkeland LI, Dahl CP, Hagelin EM, von Lueder T, Edvardsen T, Andreassen AK, Gullestad L, Aukrust P, Yndestad A, Vinge LE, Attramadal H.
Øie E, et al.
Basic Res Cardiol. 2010 Jan;105(1):89-98. doi: 10.1007/s00395-009-0070-y.
Basic Res Cardiol. 2010.
PMID: 19823891
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