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Plasma p-tau181 shows stronger network association to Alzheimer's disease dementia than neurofilament light and total tau.
Frank B, Ally M, Brekke B, Zetterberg H, Blennow K, Sugarman MA, Ashton NJ, Karikari TK, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Simkina I, Turk KW, Budson AE, O'Connor MK, Au R, Goldstein LE, Jun GR, Kowall NW, Stein TD, McKee AC, Killiany R, Qiu WQ, Stern RA, Mez J, Alosco ML. Frank B, et al. Among authors: blennow k. Alzheimers Dement. 2022 Aug;18(8):1523-1536. doi: 10.1002/alz.12508. Epub 2021 Dec 2. Alzheimers Dement. 2022. PMID: 34854549 Free PMC article.
Both total and phosphorylated tau are increased in Alzheimer's disease.
Sjögren M, Davidsson P, Tullberg M, Minthon L, Wallin A, Wikkelso C, Granérus AK, Vanderstichele H, Vanmechelen E, Blennow K. Sjögren M, et al. Among authors: blennow k. J Neurol Neurosurg Psychiatry. 2001 May;70(5):624-30. doi: 10.1136/jnnp.70.5.624. J Neurol Neurosurg Psychiatry. 2001. PMID: 11309456 Free PMC article.
CSF markers for incipient Alzheimer's disease.
Blennow K, Hampel H. Blennow K, et al. Lancet Neurol. 2003 Oct;2(10):605-13. doi: 10.1016/s1474-4422(03)00530-1. Lancet Neurol. 2003. PMID: 14505582 Review.
2,088 results