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A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity.
Sci Immunol. 2021 Dec 3;6(66):eabf1152. doi: 10.1126/sciimmunol.abf1152. Epub 2021 Dec 3.
Sci Immunol. 2021.
PMID: 34860581
Free PMC article.
Long-primed germinal centres with enduring affinity maturation and clonal migration.
Lee JH, Sutton HJ, Cottrell CA, Phung I, Ozorowski G, Sewall LM, Nedellec R, Nakao C, Silva M, Richey ST, Torres JL, Lee WH, Georgeson E, Kubitz M, Hodges S, Mullen TM, Adachi Y, Cirelli KM, Kaur A, Allers C, Fahlberg M, Grasperge BF, Dufour JP, Schiro F, Aye PP, Kalyuzhniy O, Liguori A, Carnathan DG, Silvestri G, Shen X, Montefiori DC, Veazey RS, Ward AB, Hangartner L, Burton DR, Irvine DJ, Schief WR, Crotty S.
Lee JH, et al. Among authors: phung i.
Nature. 2022 Sep;609(7929):998-1004. doi: 10.1038/s41586-022-05216-9. Epub 2022 Sep 21.
Nature. 2022.
PMID: 36131022
Free PMC article.
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Affinity gaps among B cells in germinal centers drive the selection of MPER precursors.
Ray R, Schiffner T, Wang X, Yan Y, Rantalainen K, Lee CD, Parikh S, Reyes RA, Dale GA, Lin YC, Pecetta S, Giguere S, Swanson O, Kratochvil S, Melzi E, Phung I, Madungwe L, Kalyuzhniy O, Warner J, Weldon SR, Tingle R, Lamperti E, Kirsch KH, Phelps N, Georgeson E, Adachi Y, Kubitz M, Nair U, Crotty S, Wilson IA, Schief WR, Batista FD.
Ray R, et al. Among authors: phung i.
Nat Immunol. 2024 May 30. doi: 10.1038/s41590-024-01844-7. Online ahead of print.
Nat Immunol. 2024.
PMID: 38816616
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Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Schiffner T, Phung I, Ray R, Irimia A, Tian M, Swanson O, Lee JH, Lee CD, Marina-Zárate E, Cho SY, Huang J, Ozorowski G, Skog PD, Serra AM, Rantalainen K, Allen JD, Baboo S, Rodriguez OL, Himansu S, Zhou J, Hurtado J, Flynn CT, McKenney K, Havenar-Daughton C, Saha S, Shields K, Schulze S, Smith ML, Liang CH, Toy L, Pecetta S, Lin YC, Willis JR, Sesterhenn F, Kulp DW, Hu X, Cottrell CA, Zhou X, Ruiz J, Wang X, Nair U, Kirsch KH, Cheng HL, Davis J, Kalyuzhniy O, Liguori A, Diedrich JK, Ngo JT, Lewis V, Phelps N, Tingle RD, Spencer S, Georgeson E, Adachi Y, Kubitz M, Eskandarzadeh S, Elsliger MA, Amara RR, Landais E, Briney B, Burton DR, Carnathan DG, Silvestri G, Watson CT, Yates JR 3rd, Paulson JC, Crispin M, Grigoryan G, Ward AB, Sok D, Alt FW, Wilson IA, Batista FD, Crotty S, Schief WR.
Schiffner T, et al. Among authors: phung i.
Nat Immunol. 2024 May 30. doi: 10.1038/s41590-024-01833-w. Online ahead of print.
Nat Immunol. 2024.
PMID: 38816615
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Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates.
Steichen JM, Phung I, Salcedo E, Ozorowski G, Willis JR, Baboo S, Liguori A, Cottrell CA, Torres JL, Madden PJ, Ma KM, Sutton HJ, Lee JH, Kalyuzhniy O, Allen JD, Rodriguez OL, Adachi Y, Mullen TM, Georgeson E, Kubitz M, Burns A, Barman S, Mopuri R, Metz A, Altheide TK, Diedrich JK, Saha S, Shields K, Schultze SE, Smith ML, Schiffner T, Burton DR, Watson CT, Bosinger SE, Crispin M, Yates JR 3rd, Paulson JC, Ward AB, Sok D, Crotty S, Schief WR.
Steichen JM, et al. Among authors: phung i.
Science. 2024 May 17;384(6697):eadj8321. doi: 10.1126/science.adj8321. Epub 2024 May 17.
Science. 2024.
PMID: 38753769
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A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates.
Phung I, Rodrigues KA, Marina-Zárate E, Maiorino L, Pahar B, Lee WH, Melo M, Kaur A, Allers C, Fahlberg M, Grasperge BF, Dufour JP, Schiro F, Aye PP, Lopez PG, Torres JL, Ozorowski G, Eskandarzadeh S, Kubitz M, Georgeson E, Groschel B, Nedellec R, Bick M, Kaczmarek Michaels K, Gao H, Shen X, Carnathan DG, Silvestri G, Montefiori DC, Ward AB, Hangartner L, Veazey RS, Burton DR, Schief WR, Irvine DJ, Crotty S.
Phung I, et al.
Nat Commun. 2023 Nov 4;14(1):7107. doi: 10.1038/s41467-023-42923-x.
Nat Commun. 2023.
PMID: 37925510
Free PMC article.
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Author Correction: Long-primed germinal centres with enduring affinity maturation and clonal migration.
Lee JH, Sutton HJ, Cottrell CA, Phung I, Ozorowski G, Sewall LM, Nedellec R, Nakao C, Silva M, Richey ST, Torres JL, Lee WH, Georgeson E, Kubitz M, Hodges S, Mullen TM, Adachi Y, Cirelli KM, Kaur A, Allers C, Fahlberg M, Grasperge BF, Dufour JP, Schiro F, Aye PP, Kalyuzhniy O, Liguori A, Carnathan DG, Silvestri G, Shen X, Montefiori DC, Veazey RS, Ward AB, Hangartner L, Burton DR, Irvine DJ, Schief WR, Crotty S.
Lee JH, et al. Among authors: phung i.
Nature. 2023 Feb;614(7949):E43. doi: 10.1038/s41586-023-05741-1.
Nature. 2023.
PMID: 36717721
Free PMC article.
No abstract available.
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An oncogenic mutant of RHEB, RHEB Y35N, exhibits an altered interaction with BRAF resulting in cancer transformation.
Heard JJ, Phung I, Potes MI, Tamanoi F.
Heard JJ, et al. Among authors: phung i.
BMC Cancer. 2018 Jan 10;18(1):69. doi: 10.1186/s12885-017-3938-5.
BMC Cancer. 2018.
PMID: 29320991
Free PMC article.
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