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Two cell line models to study multiorganic metastasis and immunotherapy in lung squamous cell carcinoma.
Valencia K, Sainz C, Bértolo C, de Biurrun G, Agorreta J, Azpilikueta A, Larrayoz M, Bosco G, Zandueta C, Redrado M, Redín E, Exposito F, Serrano D, Echepare M, Ajona D, Melero I, Pio R, Thomas R, Calvo A, Montuenga LM. Valencia K, et al. Among authors: agorreta j. Dis Model Mech. 2022 Jan 1;15(1):dmm049137. doi: 10.1242/dmm.049137. Epub 2022 Jan 31. Dis Model Mech. 2022. PMID: 34870316 Free PMC article.
Successful Immunotherapy against a Transplantable Mouse Squamous Lung Carcinoma with Anti-PD-1 and Anti-CD137 Monoclonal Antibodies.
Azpilikueta A, Agorreta J, Labiano S, Pérez-Gracia JL, Sánchez-Paulete AR, Aznar MA, Ajona D, Gil-Bazo I, Larrayoz M, Teijeira A, Rodriguez-Ruiz ME, Pio R, Montuenga LM, Melero I. Azpilikueta A, et al. Among authors: agorreta j. J Thorac Oncol. 2016 Apr;11(4):524-36. doi: 10.1016/j.jtho.2016.01.013. Epub 2016 Feb 1. J Thorac Oncol. 2016. PMID: 26845193 Free article.
SRC family kinase (SFK) inhibitor dasatinib improves the antitumor activity of anti-PD-1 in NSCLC models by inhibiting Treg cell conversion and proliferation.
Redin E, Garmendia I, Lozano T, Serrano D, Senent Y, Redrado M, Villalba M, De Andrea CE, Exposito F, Ajona D, Ortiz-Espinosa S, Remirez A, Bertolo C, Sainz C, Garcia-Pedrero J, Pio R, Lasarte J, Agorreta J, Montuenga LM, Calvo A. Redin E, et al. Among authors: agorreta j. J Immunother Cancer. 2021 Mar;9(3):e001496. doi: 10.1136/jitc-2020-001496. J Immunother Cancer. 2021. PMID: 33658304 Free PMC article.
DSTYK inhibition increases the sensitivity of lung cancer cells to T cell-mediated cytotoxicity.
Valencia K, Echepare M, Teijeira Á, Pasquier A, Bértolo C, Sainz C, Tamayo I, Picabea B, Bosco G, Thomas R, Agorreta J, López-Picazo JM, Frigola J, Amat R, Calvo A, Felip E, Melero I, Montuenga LM. Valencia K, et al. Among authors: agorreta j. J Exp Med. 2022 Dec 5;219(12):e20220726. doi: 10.1084/jem.20220726. Epub 2022 Sep 28. J Exp Med. 2022. PMID: 36169652 Free PMC article.
Inhibitor of differentiation-1 as a novel prognostic factor in NSCLC patients with adenocarcinoma histology and its potential contribution to therapy resistance.
Ponz-Sarvisé M, Nguewa PA, Pajares MJ, Agorreta J, Lozano MD, Redrado M, Pio R, Behrens C, Wistuba II, García-Franco CE, García-Foncillas J, Montuenga LM, Calvo A, Gil-Bazo I. Ponz-Sarvisé M, et al. Among authors: agorreta j. Clin Cancer Res. 2011 Jun 15;17(12):4155-66. doi: 10.1158/1078-0432.CCR-10-3381. Epub 2011 May 3. Clin Cancer Res. 2011. PMID: 21540238
Inhibition of collagen receptor discoidin domain receptor-1 (DDR1) reduces cell survival, homing, and colonization in lung cancer bone metastasis.
Valencia K, Ormazábal C, Zandueta C, Luis-Ravelo D, Antón I, Pajares MJ, Agorreta J, Montuenga LM, Martínez-Canarias S, Leitinger B, Lecanda F. Valencia K, et al. Among authors: agorreta j. Clin Cancer Res. 2012 Feb 15;18(4):969-80. doi: 10.1158/1078-0432.CCR-11-1686. Epub 2012 Jan 5. Clin Cancer Res. 2012. PMID: 22223527
Expression of tumor-derived vascular endothelial growth factor and its receptors is associated with outcome in early squamous cell carcinoma of the lung.
Pajares MJ, Agorreta J, Larrayoz M, Vesin A, Ezponda T, Zudaire I, Torre W, Lozano MD, Brambilla E, Brambilla C, Wistuba II, Behrens C, Timsit JF, Pio R, Field JK, Montuenga LM. Pajares MJ, et al. Among authors: agorreta j. J Clin Oncol. 2012 Apr 1;30(10):1129-36. doi: 10.1200/JCO.2011.37.4231. Epub 2012 Feb 21. J Clin Oncol. 2012. PMID: 22355056 Free PMC article.
Receptor of activated protein C promotes metastasis and correlates with clinical outcome in lung adenocarcinoma.
Antón I, Molina E, Luis-Ravelo D, Zandueta C, Valencia K, Ormazabal C, Martínez-Canarias S, Perurena N, Pajares MJ, Agorreta J, Montuenga LM, Segura V, Wistuba II, De Las Rivas J, Hermida J, Lecanda F. Antón I, et al. Among authors: agorreta j. Am J Respir Crit Care Med. 2012 Jul 1;186(1):96-105. doi: 10.1164/rccm.201110-1826OC. Epub 2012 Mar 29. Am J Respir Crit Care Med. 2012. PMID: 22461368 Free PMC article.
44 results