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Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood.
Kariotis S, Jammeh E, Swietlik EM, Pickworth JA, Rhodes CJ, Otero P, Wharton J, Iremonger J, Dunning MJ, Pandya D, Mascarenhas TS, Errington N, Thompson AAR, Romanoski CE, Rischard F, Garcia JGN, Yuan JX, An TS, Desai AA, Coghlan G, Lordan J, Corris PA, Howard LS, Condliffe R, Kiely DG, Church C, Pepke-Zaba J, Toshner M, Wort S, Gräf S, Morrell NW, Wilkins MR, Lawrie A, Wang D; UK National PAH Cohort Study Consortium. Kariotis S, et al. Among authors: desai aa. Nat Commun. 2021 Dec 7;12(1):7104. doi: 10.1038/s41467-021-27326-0. Nat Commun. 2021. PMID: 34876579 Free PMC article.
Asymmetric Dimethylarginine Stimulates Akt1 Phosphorylation via Heat Shock Protein 70-Facilitated Carboxyl-Terminal Modulator Protein Degradation in Pulmonary Arterial Endothelial Cells.
Sun X, Kellner M, Desai AA, Wang T, Lu Q, Kangath A, Qu N, Klinger C, Fratz S, Yuan JX, Jacobson JR, Garcia JG, Rafikov R, Fineman JR, Black SM. Sun X, et al. Among authors: desai aa. Am J Respir Cell Mol Biol. 2016 Aug;55(2):275-87. doi: 10.1165/rcmb.2015-0185OC. Am J Respir Cell Mol Biol. 2016. PMID: 26959555 Free PMC article.
Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension.
Tang H, Yamamura A, Yamamura H, Song S, Fraidenburg DR, Chen J, Gu Y, Pohl NM, Zhou T, Jiménez-Pérez L, Ayon RJ, Desai AA, Goltzman D, Rischard F, Khalpey Z, Black SM, Garcia JG, Makino A, Yuan JX. Tang H, et al. Among authors: desai aa. Am J Physiol Lung Cell Mol Physiol. 2016 May 1;310(9):L846-59. doi: 10.1152/ajplung.00050.2016. Epub 2016 Mar 11. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 26968768 Free PMC article.
Endothelial cell signaling and ventilator-induced lung injury: molecular mechanisms, genomic analyses, and therapeutic targets.
Wang T, Gross C, Desai AA, Zemskov E, Wu X, Garcia AN, Jacobson JR, Yuan JX, Garcia JG, Black SM. Wang T, et al. Among authors: desai aa. Am J Physiol Lung Cell Mol Physiol. 2017 Apr 1;312(4):L452-L476. doi: 10.1152/ajplung.00231.2016. Epub 2016 Dec 15. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 27979857 Free PMC article. Review.
Capsaicin-induced Ca2+ signaling is enhanced via upregulated TRPV1 channels in pulmonary artery smooth muscle cells from patients with idiopathic PAH.
Song S, Ayon RJ, Yamamura A, Yamamura H, Dash S, Babicheva A, Tang H, Sun X, Cordery AG, Khalpey Z, Black SM, Desai AA, Rischard F, McDermott KM, Garcia JG, Makino A, Yuan JX. Song S, et al. Among authors: desai aa. Am J Physiol Lung Cell Mol Physiol. 2017 Mar 1;312(3):L309-L325. doi: 10.1152/ajplung.00357.2016. Epub 2016 Dec 15. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 27979859 Free PMC article.
223 results