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Validated biomarker assays confirm that ARID1A loss is confounded with MMR deficiency, CD8+ TIL infiltration, and provides no independent prognostic value in endometriosis-associated ovarian carcinomas.
Heinze K, Nazeran TM, Lee S, Krämer P, Cairns ES, Chiu DS, Leung SC, Kang EY, Meagher NS, Kennedy CJ, Boros J, Kommoss F, Vollert HW, Heitz F, du Bois A, Harter P, Grube M, Kraemer B, Staebler A, Kommoss FK, Heublein S, Sinn HP, Singh N, Laslavic A, Elishaev E, Olawaiye A, Moysich K, Modugno F, Sharma R, Brand AH, Harnett PR, DeFazio A, Fortner RT, Lubinski J, Lener M, Tołoczko-Grabarek A, Cybulski C, Gronwald H, Gronwald J, Coulson P, El-Bahrawy MA, Jones ME, Schoemaker MJ, Swerdlow AJ, Gorringe KL, Campbell I, Cook L, Gayther SA, Carney ME, Shvetsov YB, Hernandez BY, Wilkens LR, Goodman MT, Mateoiu C, Linder A, Sundfeldt K, Kelemen LE, Gentry-Maharaj A, Widschwendter M, Menon U, Bolton KL, Alsop J, Shah M, Jimenez-Linan M, Pharoah PD, Brenton JD, Cushing-Haugen KL, Harris HR, Doherty JA, Gilks B, Ghatage P, Huntsman DG, Nelson GS, Tinker AV, Lee CH, Goode EL, Nelson BH, Ramus SJ, Kommoss S, Talhouk A, Köbel M, Anglesio MS. Heinze K, et al. Among authors: staebler a. J Pathol. 2022 Apr;256(4):388-401. doi: 10.1002/path.5849. Epub 2022 Feb 7. J Pathol. 2022. PMID: 34897700 Free PMC article.
SOX2 amplification is a common event in squamous cell carcinomas of different organ sites.
Maier S, Wilbertz T, Braun M, Scheble V, Reischl M, Mikut R, Menon R, Nikolov P, Petersen K, Beschorner C, Moch H, Kakies C, Protzel C, Bauer J, Soltermann A, Fend F, Staebler A, Lengerke C, Perner S. Maier S, et al. Among authors: staebler a. Hum Pathol. 2011 Aug;42(8):1078-88. doi: 10.1016/j.humpath.2010.11.010. Epub 2011 Feb 21. Hum Pathol. 2011. PMID: 21334718
SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer.
Wilbertz T, Wagner P, Petersen K, Stiedl AC, Scheble VJ, Maier S, Reischl M, Mikut R, Altorki NK, Moch H, Fend F, Staebler A, Bass AJ, Meyerson M, Rubin MA, Soltermann A, Lengerke C, Perner S. Wilbertz T, et al. Among authors: staebler a. Mod Pathol. 2011 Jul;24(7):944-53. doi: 10.1038/modpathol.2011.49. Epub 2011 Apr 1. Mod Pathol. 2011. PMID: 21460799 Free article.
SOX2 expression and prognostic significance in ovarian carcinoma.
Pham DL, Scheble V, Bareiss P, Fischer A, Beschorner C, Adam A, Bachmann C, Neubauer H, Boesmueller H, Kanz L, Wallwiener D, Fend F, Lengerke C, Perner S, Fehm T, Staebler A. Pham DL, et al. Among authors: staebler a. Int J Gynecol Pathol. 2013 Jul;32(4):358-67. doi: 10.1097/PGP.0b013e31826a642b. Int J Gynecol Pathol. 2013. PMID: 23722508
Polymerase Epsilon Exonuclease Domain Mutations in Ovarian Endometrioid Carcinoma.
Hoang LN, McConechy MK, Köbel M, Anglesio M, Senz J, Maassen M, Kommoss S, Meng B, Postovit L, Kelemen LE, Staebler A, Brucker S, Krämer B, McAlpine JN, Gilks CB, Huntsman DG, Lee CH. Hoang LN, et al. Among authors: staebler a. Int J Gynecol Cancer. 2015 Sep;25(7):1187-93. doi: 10.1097/IGC.0000000000000492. Int J Gynecol Cancer. 2015. PMID: 26166557
Synchronous Endometrial and Ovarian Carcinomas: Evidence of Clonality.
Anglesio MS, Wang YK, Maassen M, Horlings HM, Bashashati A, Senz J, Mackenzie R, Grewal DS, Li-Chang H, Karnezis AN, Sheffield BS, McConechy MK, Kommoss F, Taran FA, Staebler A, Shah SP, Wallwiener D, Brucker S, Gilks CB, Kommoss S, Huntsman DG. Anglesio MS, et al. Among authors: staebler a. J Natl Cancer Inst. 2016 Feb 1;108(6):djv428. doi: 10.1093/jnci/djv428. Print 2016 Jun. J Natl Cancer Inst. 2016. PMID: 26832771
Molecularly Defined Adult Granulosa Cell Tumor of the Ovary: The Clinical Phenotype.
McConechy MK, Färkkilä A, Horlings HM, Talhouk A, Unkila-Kallio L, van Meurs HS, Yang W, Rozenberg N, Andersson N, Zaby K, Bryk S, Bützow R, Halfwerk JB, Hooijer GK, van de Vijver MJ, Buist MR, Kenter GG, Brucker SY, Krämer B, Staebler A, Bleeker MC, Heikinheimo M, Kommoss S, Blake Gilks C, Anttonen M, Huntsman DG. McConechy MK, et al. Among authors: staebler a. J Natl Cancer Inst. 2016 Jun 13;108(11):djw134. doi: 10.1093/jnci/djw134. Print 2016 Nov. J Natl Cancer Inst. 2016. PMID: 27297428 Free PMC article.
L1CAM: amending the "low-risk" category in endometrial carcinoma.
Kommoss F, Kommoss F, Grevenkamp F, Bunz AK, Taran FA, Fend F, Brucker SY, Wallwiener D, Schönfisch B, Greif K, Lax S, Staebler A, Kommoss S. Kommoss F, et al. Among authors: staebler a. J Cancer Res Clin Oncol. 2017 Feb;143(2):255-262. doi: 10.1007/s00432-016-2276-3. Epub 2016 Sep 30. J Cancer Res Clin Oncol. 2017. PMID: 27695947
157 results