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Circulating tumour DNA sequencing to determine therapeutic response and identify tumour heterogeneity in patients with paediatric solid tumours.
Stankunaite R, George SL, Gallagher L, Jamal S, Shaikh R, Yuan L, Hughes D, Proszek PZ, Carter P, Pietka G, Heide T, James C, Tari H, Lynn C, Jain N, Portela LR, Rogers T, Vaidya SJ, Chisholm JC, Carceller F, Szychot E, Mandeville H, Angelini P, Jesudason AB, Jackson M, Marshall LV, Gatz SA, Anderson J, Sottoriva A, Chesler L, Hubank M. Stankunaite R, et al. Among authors: sottoriva a. Eur J Cancer. 2022 Feb;162:209-220. doi: 10.1016/j.ejca.2021.09.042. Epub 2021 Dec 18. Eur J Cancer. 2022. PMID: 34933802 Free article.
Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial.
Khan KH, Cunningham D, Werner B, Vlachogiannis G, Spiteri I, Heide T, Mateos JF, Vatsiou A, Lampis A, Damavandi MD, Lote H, Huntingford IS, Hedayat S, Chau I, Tunariu N, Mentrasti G, Trevisani F, Rao S, Anandappa G, Watkins D, Starling N, Thomas J, Peckitt C, Khan N, Rugge M, Begum R, Hezelova B, Bryant A, Jones T, Proszek P, Fassan M, Hahne JC, Hubank M, Braconi C, Sottoriva A, Valeri N. Khan KH, et al. Among authors: sottoriva a. Cancer Discov. 2018 Oct;8(10):1270-1285. doi: 10.1158/2159-8290.CD-17-0891. Epub 2018 Aug 30. Cancer Discov. 2018. PMID: 30166348 Free PMC article. Clinical Trial.
Detecting repeated cancer evolution from multi-region tumor sequencing data.
Caravagna G, Giarratano Y, Ramazzotti D, Tomlinson I, Graham TA, Sanguinetti G, Sottoriva A. Caravagna G, et al. Among authors: sottoriva a. Nat Methods. 2018 Sep;15(9):707-714. doi: 10.1038/s41592-018-0108-x. Epub 2018 Aug 31. Nat Methods. 2018. PMID: 30171232 Free PMC article.
Reply to 'Neutral tumor evolution?'.
Heide T, Zapata L, Williams MJ, Werner B, Caravagna G, Barnes CP, Graham TA, Sottoriva A. Heide T, et al. Among authors: sottoriva a. Nat Genet. 2018 Dec;50(12):1633-1637. doi: 10.1038/s41588-018-0256-z. Nat Genet. 2018. PMID: 30374073 No abstract available.
Resolving genetic heterogeneity in cancer.
Turajlic S, Sottoriva A, Graham T, Swanton C. Turajlic S, et al. Among authors: sottoriva a. Nat Rev Genet. 2019 Jul;20(7):404-416. doi: 10.1038/s41576-019-0114-6. Nat Rev Genet. 2019. PMID: 30918367 Review.
Measuring single cell divisions in human tissues from multi-region sequencing data.
Werner B, Case J, Williams MJ, Chkhaidze K, Temko D, Fernández-Mateos J, Cresswell GD, Nichol D, Cross W, Spiteri I, Huang W, Tomlinson IPM, Barnes CP, Graham TA, Sottoriva A. Werner B, et al. Among authors: sottoriva a. Nat Commun. 2020 Feb 25;11(1):1035. doi: 10.1038/s41467-020-14844-6. Nat Commun. 2020. PMID: 32098957 Free PMC article.
71 results