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Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide.
Nat Med. 2022 Jan;28(1):117-124. doi: 10.1038/s41591-021-01557-6. Epub 2021 Dec 23.
Nat Med. 2022.
PMID: 34949835
Free PMC article.
Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts.
Shin M, Chan IL, Cao Y, Gruntman AM, Lee J, Sousa J, Rodríguez TC, Echeverria D, Devi G, Debacker AJ, Moazami MP, Krishnamurthy PM, Rembetsy-Brown JM, Kelly K, Yukselen O, Donnard E, Parsons TJ, Khvorova A, Sontheimer EJ, Maehr R, Garber M, Watts JK.
Shin M, et al. Among authors: moazami mp.
Nucleic Acids Res. 2022 Aug 26;50(15):8418-8430. doi: 10.1093/nar/gkac630.
Nucleic Acids Res. 2022.
PMID: 35920332
Free PMC article.
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Hybrid Aptamer-Molecularly Imprinted Polymer (aptaMIP) Nanoparticles from Protein Recognition-A Trypsin Model.
Sullivan MV, Clay O, Moazami MP, Watts JK, Turner NW.
Sullivan MV, et al. Among authors: moazami mp.
Macromol Biosci. 2021 May;21(5):e2100002. doi: 10.1002/mabi.202100002. Epub 2021 Mar 24.
Macromol Biosci. 2021.
PMID: 33760365
Free article.
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Locked Nucleic Acid Gapmers and Conjugates Potently Silence ADAM33, an Asthma-Associated Metalloprotease with Nuclear-Localized mRNA.
Pendergraff HM, Krishnamurthy PM, Debacker AJ, Moazami MP, Sharma VK, Niitsoo L, Yu Y, Tan YN, Haitchi HM, Watts JK.
Pendergraff HM, et al. Among authors: moazami mp.
Mol Ther Nucleic Acids. 2017 Sep 15;8:158-168. doi: 10.1016/j.omtn.2017.06.012. Epub 2017 Jun 21.
Mol Ther Nucleic Acids. 2017.
PMID: 28918018
Free PMC article.
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Efficient Gene Silencing in Brain Tumors with Hydrophobically Modified siRNAs.
Osborn MF, Coles AH, Golebiowski D, Echeverria D, Moazami MP, Watts JK, Sena-Esteves M, Khvorova A.
Osborn MF, et al. Among authors: moazami mp.
Mol Cancer Ther. 2018 Jun;17(6):1251-1258. doi: 10.1158/1535-7163.MCT-17-1144. Epub 2018 Apr 13.
Mol Cancer Ther. 2018.
PMID: 29654062
Free PMC article.
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RNase-H-mediated silencing in the CNS proves predictably nontrivial.
Moazami MP, Wood MJA.
Moazami MP, et al.
Med. 2022 Nov 11;3(11):733-734. doi: 10.1016/j.medj.2022.10.004.
Med. 2022.
PMID: 36370693
Free article.
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