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Real-world application of tumor mutational burden-high (TMB-high) and microsatellite instability (MSI) confirms their utility as immunotherapy biomarkers.
Palmeri M, Mehnert J, Silk AW, Jabbour SK, Ganesan S, Popli P, Riedlinger G, Stephenson R, de Meritens AB, Leiser A, Mayer T, Chan N, Spencer K, Girda E, Malhotra J, Chan T, Subbiah V, Groisberg R. Palmeri M, et al. Among authors: spencer k. ESMO Open. 2022 Feb;7(1):100336. doi: 10.1016/j.esmoop.2021.100336. Epub 2021 Dec 23. ESMO Open. 2022. PMID: 34953399 Free PMC article.
Ipilimumab Therapy in Patients With Advanced Melanoma and Preexisting Autoimmune Disorders.
Johnson DB, Sullivan RJ, Ott PA, Carlino MS, Khushalani NI, Ye F, Guminski A, Puzanov I, Lawrence DP, Buchbinder EI, Mudigonda T, Spencer K, Bender C, Lee J, Kaufman HL, Menzies AM, Hassel JC, Mehnert JM, Sosman JA, Long GV, Clark JI. Johnson DB, et al. Among authors: spencer k. JAMA Oncol. 2016 Feb;2(2):234-40. doi: 10.1001/jamaoncol.2015.4368. JAMA Oncol. 2016. PMID: 26633184
Multiple primary malignancies in patients with anal squamous cell carcinoma.
Li D, Yegya-Raman N, Kim S, Ganesan S, Sayan M, August D, Spencer K, Hathout L, Maloney-Patel N, Malhotra U, Yue NJ, Jabbour SK. Li D, et al. Among authors: spencer k. J Gastrointest Oncol. 2018 Oct;9(5):853-857. doi: 10.21037/jgo.2018.06.07. J Gastrointest Oncol. 2018. PMID: 30505585 Free PMC article.
Adjuvant therapeutic strategies for resectable pancreatic adenocarcinoma.
Yegya-Raman N, Shah MM, Grandhi MS, Poplin E, August DA, Kennedy TJ, Malhotra U, Spencer KR, Carpizo DR, Jabbour SK. Yegya-Raman N, et al. Among authors: spencer kr. Ann Pancreat Cancer. 2018 Aug;1:20. doi: 10.21037/apc.2018.07.05. Epub 2018 Aug 6. Ann Pancreat Cancer. 2018. PMID: 30687847 Free PMC article.
A phase I trial of MK-2206 and hydroxychloroquine in patients with advanced solid tumors.
Mehnert JM, Kaveney AD, Malhotra J, Spencer K, Portal D, Goodin S, Tan AR, Aisner J, Moss RA, Lin H, Bertino JR, Gibbon D, Doyle LA, White EP, Stein MN. Mehnert JM, et al. Among authors: spencer k. Cancer Chemother Pharmacol. 2019 Oct;84(4):899-907. doi: 10.1007/s00280-019-03919-x. Epub 2019 Aug 28. Cancer Chemother Pharmacol. 2019. PMID: 31463691 Clinical Trial.
1,024 results