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Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism.
García-Silva S, Benito-Martín A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÁ, Torres-Ruiz R, Rodríguez-Perales S, Martínez L, Pérez-Martínez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, Martínez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, Megías D, Mehrara BJ, Lyden D, Peinado H. García-Silva S, et al. Among authors: peinado h. Nat Cancer. 2021 Dec;2(12):1387-1405. doi: 10.1038/s43018-021-00272-y. Epub 2021 Nov 25. Nat Cancer. 2021. PMID: 34957415 Free PMC article.
Inflammation joins the "niche".
Peinado H, Rafii S, Lyden D. Peinado H, et al. Cancer Cell. 2008 Nov 4;14(5):347-9. doi: 10.1016/j.ccr.2008.10.012. Cancer Cell. 2008. PMID: 18977322 Free PMC article.
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Peinado H, Alečković M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D. Peinado H, et al. Nat Med. 2012 Jun;18(6):883-91. doi: 10.1038/nm.2753. Nat Med. 2012. PMID: 22635005 Free PMC article.
Mutation of SIMPLE in Charcot-Marie-Tooth 1C alters production of exosomes.
Zhu H, Guariglia S, Yu RY, Li W, Brancho D, Peinado H, Lyden D, Salzer J, Bennett C, Chow CW. Zhu H, et al. Among authors: peinado h. Mol Biol Cell. 2013 Jun;24(11):1619-37, S1-3. doi: 10.1091/mbc.E12-07-0544. Epub 2013 Apr 10. Mol Biol Cell. 2013. PMID: 23576546 Free PMC article.
The perivascular niche regulates breast tumour dormancy.
Ghajar CM, Peinado H, Mori H, Matei IR, Evason KJ, Brazier H, Almeida D, Koller A, Hajjar KA, Stainier DY, Chen EI, Lyden D, Bissell MJ. Ghajar CM, et al. Among authors: peinado h. Nat Cell Biol. 2013 Jul;15(7):807-17. doi: 10.1038/ncb2767. Epub 2013 Jun 2. Nat Cell Biol. 2013. PMID: 23728425 Free PMC article.
Gasdermin-B promotes invasion and metastasis in breast cancer cells.
Hergueta-Redondo M, Sarrió D, Molina-Crespo Á, Megias D, Mota A, Rojo-Sebastian A, García-Sanz P, Morales S, Abril S, Cano A, Peinado H, Moreno-Bueno G. Hergueta-Redondo M, et al. Among authors: peinado h. PLoS One. 2014 Mar 27;9(3):e90099. doi: 10.1371/journal.pone.0090099. eCollection 2014. PLoS One. 2014. PMID: 24675552 Free PMC article.
120 results