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GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity.
Heitzeneder S, Bosse KR, Zhu Z, Zhelev D, Majzner RG, Radosevich MT, Dhingra S, Sotillo E, Buongervino S, Pascual-Pasto G, Garrigan E, Xu P, Huang J, Salzer B, Delaidelli A, Raman S, Cui H, Martinez B, Bornheimer SJ, Sahaf B, Alag A, Fetahu IS, Hasselblatt M, Parker KR, Anbunathan H, Hwang J, Huang M, Sakamoto K, Lacayo NJ, Klysz DD, Theruvath J, Vilches-Moure JG, Satpathy AT, Chang HY, Lehner M, Taschner-Mandl S, Julien JP, Sorensen PH, Dimitrov DS, Maris JM, Mackall CL. Heitzeneder S, et al. Among authors: zhu z. Cancer Cell. 2022 Jan 10;40(1):53-69.e9. doi: 10.1016/j.ccell.2021.12.005. Epub 2021 Dec 30. Cancer Cell. 2022. PMID: 34971569 Free PMC article.
Construction of a human antibody domain (VH) library.
Chen W, Zhu Z, Xiao X, Dimitrov DS. Chen W, et al. Among authors: zhu z. Methods Mol Biol. 2009;525:81-99, xiii. doi: 10.1007/978-1-59745-554-1_4. Methods Mol Biol. 2009. PMID: 19252835 Free PMC article.
Multiple site-specific in vitro labeling of single-chain antibody.
Ramakrishnan B, Boeggeman E, Manzoni M, Zhu Z, Loomis K, Puri A, Dimitrov DS, Qasba PK. Ramakrishnan B, et al. Among authors: zhu z. Bioconjug Chem. 2009 Jul;20(7):1383-9. doi: 10.1021/bc900149r. Bioconjug Chem. 2009. PMID: 19507852 Free PMC article.
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