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Deletion of kif3a in CK19 positive cells leads to primary cilia loss, biliary cell proliferation and cystic liver lesions in TAA-treated mice.
Chen J, Cheng NC, Boland JA, Liu K, Kench JG, Watkins DN, Ferreira-Gonzalez S, Forbes SJ, McCaughan GW. Chen J, et al. Among authors: boland ja. Biochim Biophys Acta Mol Basis Dis. 2022 Apr 1;1868(4):166335. doi: 10.1016/j.bbadis.2021.166335. Epub 2021 Dec 30. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 34973373 Free article.
Widespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease.
Grzelak CA, Sigglekow ND, Tirnitz-Parker JE, Hamson EJ, Warren A, Maneck B, Chen J, Patkunanathan B, Boland J, Cheng R, Shackel NA, Seth D, Bowen DG, Martelotto LG, Watkins DN, McCaughan GW. Grzelak CA, et al. PLoS One. 2017 Feb 10;12(2):e0171480. doi: 10.1371/journal.pone.0171480. eCollection 2017. PLoS One. 2017. PMID: 28187190 Free PMC article.
Liver-specific deletion of miR-181ab1 reduces liver tumour progression via upregulation of CBX7.
Chen J, Zhao Y, Zhang F, Li J, Boland JA, Cheng NC, Liu K, Tiffen JC, Bertolino P, Bowen DG, Krueger A, Lisowski L, Alexander IE, Vadas MA, El-Omar E, Gamble JR, McCaughan GW. Chen J, et al. Among authors: boland ja. Cell Mol Life Sci. 2022 Jul 22;79(8):443. doi: 10.1007/s00018-022-04452-6. Cell Mol Life Sci. 2022. PMID: 35867177 Free PMC article.
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference.
El Bakali J, Blaszczyk M, Evans JC, Boland JA, McCarthy WJ, Fathoni I, Dias MVB, Johnson EO, Coyne AG, Mizrahi V, Blundell TL, Abell C, Spry C. El Bakali J, et al. Among authors: boland ja. Angew Chem Weinheim Bergstr Ger. 2023 Apr 17;135(17):e202300221. doi: 10.1002/ange.202300221. Epub 2023 Mar 13. Angew Chem Weinheim Bergstr Ger. 2023. PMID: 38515507 Free PMC article.
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference.
El Bakali J, Blaszczyk M, Evans JC, Boland JA, McCarthy WJ, Fathoni I, Dias MVB, Johnson EO, Coyne AG, Mizrahi V, Blundell TL, Abell C, Spry C. El Bakali J, et al. Among authors: boland ja. Angew Chem Int Ed Engl. 2023 Apr 17;62(17):e202300221. doi: 10.1002/anie.202300221. Epub 2023 Mar 13. Angew Chem Int Ed Engl. 2023. PMID: 36757665 Free PMC article.