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Increased energy demand from anabolic-catabolic processes drives β-lactam antibiotic lethality.
Lobritz MA, Andrews IW, Braff D, Porter CBM, Gutierrez A, Furuta Y, Cortes LBG, Ferrante T, Bening SC, Wong F, Gruber C, Bakerlee CW, Lambert G, Walker GC, Dwyer DJ, Collins JJ. Lobritz MA, et al. Among authors: bening sc. Cell Chem Biol. 2022 Feb 17;29(2):276-286.e4. doi: 10.1016/j.chembiol.2021.12.010. Epub 2022 Jan 5. Cell Chem Biol. 2022. PMID: 34990601 Free PMC article.
Antibiotic efficacy-context matters.
Yang JH, Bening SC, Collins JJ. Yang JH, et al. Among authors: bening sc. Curr Opin Microbiol. 2017 Oct;39:73-80. doi: 10.1016/j.mib.2017.09.002. Epub 2017 Oct 16. Curr Opin Microbiol. 2017. PMID: 29049930 Free PMC article. Review.