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Epigenome-wide meta-analysis of PTSD symptom severity in three military cohorts implicates DNA methylation changes in genes involved in immune system and oxidative stress.
Katrinli S, Maihofer AX, Wani AH, Pfeiffer JR, Ketema E, Ratanatharathorn A, Baker DG, Boks MP, Geuze E, Kessler RC, Risbrough VB, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Logue MW, Nievergelt CM, Smith AK, Uddin M. Katrinli S, et al. Among authors: pfeiffer jr. Mol Psychiatry. 2022 Mar;27(3):1720-1728. doi: 10.1038/s41380-021-01398-2. Epub 2022 Jan 7. Mol Psychiatry. 2022. PMID: 34992238 Free PMC article.
Traumatic Stress Epigenetics.
Pfeiffer JR, Mutesa L, Uddin M. Pfeiffer JR, et al. Curr Behav Neurosci Rep. 2018 Mar;5(1):81-93. doi: 10.1007/s40473-018-0143-z. Epub 2018 Feb 13. Curr Behav Neurosci Rep. 2018. PMID: 30225184 Free PMC article.
Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR.
Smith AK, Ratanatharathorn A, Maihofer AX, Naviaux RK, Aiello AE, Amstadter AB, Ashley-Koch AE, Baker DG, Beckham JC, Boks MP, Bromet E, Dennis M, Galea S, Garrett ME, Geuze E, Guffanti G, Hauser MA, Katrinli S, Kilaru V, Kessler RC, Kimbrel NA, Koenen KC, Kuan PF, Li K, Logue MW, Lori A, Luft BJ, Miller MW, Naviaux JC, Nugent NR, Qin X, Ressler KJ, Risbrough VB, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Vinkers CH, Wang L, Youssef NA; INTRuST Clinical Consortium; VA Mid-Atlantic MIRECC Workgroup; PGC PTSD Epigenetics Workgroup; Uddin M, Nievergelt CM. Smith AK, et al. Nat Commun. 2020 Nov 24;11(1):5965. doi: 10.1038/s41467-020-19615-x. Nat Commun. 2020. PMID: 33235198 Free PMC article.
Blood-derived deoxyribonucleic acid methylation clusters associate with adverse social exposures and endophenotypes of stress-related psychiatric illness in a trauma-exposed cohort of women.
Pfeiffer JR, van Rooij SJH, Mekawi Y, Fani N, Jovanovic T, Michopoulos V, Smith AK, Stevens JS, Uddin M. Pfeiffer JR, et al. Front Psychiatry. 2022 Nov 3;13:892302. doi: 10.3389/fpsyt.2022.892302. eCollection 2022. Front Psychiatry. 2022. PMID: 36405926 Free PMC article.
74 results