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Pooled genetic perturbation screens with image-based phenotypes.
Feldman D, Funk L, Le A, Carlson RJ, Leiken MD, Tsai F, Soong B, Singh A, Blainey PC. Feldman D, et al. Among authors: blainey pc. Nat Protoc. 2022 Feb;17(2):476-512. doi: 10.1038/s41596-021-00653-8. Epub 2022 Jan 12. Nat Protoc. 2022. PMID: 35022620 Free PMC article. Review.
Vaginal Lactobacillus fatty acid response mechanisms reveal a novel strategy for bacterial vaginosis treatment.
Zhu M, Frank MW, Radka CD, Jeanfavre S, Tse MW, Pacheco JA, Pierce K, Deik A, Xu J, Hussain S, Hussain FA, Xulu N, Khan N, Pillay V, Dong KL, Ndung'u T, Clish CB, Rock CO, Blainey PC, Bloom SM, Kwon DS. Zhu M, et al. Among authors: blainey pc. bioRxiv [Preprint]. 2023 Dec 30:2023.12.30.573720. doi: 10.1101/2023.12.30.573720. bioRxiv. 2023. PMID: 38234804 Free PMC article. Preprint.
Mobile genes in the human microbiome are structured from global to individual scales.
Brito IL, Yilmaz S, Huang K, Xu L, Jupiter SD, Jenkins AP, Naisilisili W, Tamminen M, Smillie CS, Wortman JR, Birren BW, Xavier RJ, Blainey PC, Singh AK, Gevers D, Alm EJ. Brito IL, et al. Among authors: blainey pc. Nature. 2016 Jul 21;535(7612):435-439. doi: 10.1038/nature18927. Epub 2016 Jul 13. Nature. 2016. PMID: 27409808 Free PMC article.
Optical Pooled Screens in Human Cells.
Feldman D, Singh A, Schmid-Burgk JL, Carlson RJ, Mezger A, Garrity AJ, Zhang F, Blainey PC. Feldman D, et al. Among authors: blainey pc. Cell. 2019 Oct 17;179(3):787-799.e17. doi: 10.1016/j.cell.2019.09.016. Cell. 2019. PMID: 31626775 Free PMC article.
Massively multiplexed nucleic acid detection with Cas13.
Ackerman CM, Myhrvold C, Thakku SG, Freije CA, Metsky HC, Yang DK, Ye SH, Boehm CK, Kosoko-Thoroddsen TF, Kehe J, Nguyen TG, Carter A, Kulesa A, Barnes JR, Dugan VG, Hung DT, Blainey PC, Sabeti PC. Ackerman CM, et al. Among authors: blainey pc. Nature. 2020 Jun;582(7811):277-282. doi: 10.1038/s41586-020-2279-8. Epub 2020 Apr 29. Nature. 2020. PMID: 32349121 Free PMC article.
CloneSifter: enrichment of rare clones from heterogeneous cell populations.
Feldman D, Tsai F, Garrity AJ, O'Rourke R, Brenan L, Ho P, Gonzalez E, Konermann S, Johannessen CM, Beroukhim R, Bandopadhayay P, Blainey PC. Feldman D, et al. Among authors: blainey pc. BMC Biol. 2020 Nov 24;18(1):177. doi: 10.1186/s12915-020-00911-3. BMC Biol. 2020. PMID: 33234154 Free PMC article.
The phenotypic landscape of essential human genes.
Funk L, Su KC, Ly J, Feldman D, Singh A, Moodie B, Blainey PC, Cheeseman IM. Funk L, et al. Among authors: blainey pc. Cell. 2022 Nov 23;185(24):4634-4653.e22. doi: 10.1016/j.cell.2022.10.017. Epub 2022 Nov 7. Cell. 2022. PMID: 36347254 Free PMC article.
Pooled genetic screens with image-based profiling.
Walton RT, Singh A, Blainey PC. Walton RT, et al. Among authors: blainey pc. Mol Syst Biol. 2022 Nov;18(11):e10768. doi: 10.15252/msb.202110768. Mol Syst Biol. 2022. PMID: 36366905 Free PMC article. Review.
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