Diggins K - Search Results

1

Guidelines for standardizing T-cell cytometry assays to link biomarkers, mechanisms, and disease outcomes in type 1 diabetes.

Yang JHM, Ward-Hartstonge KA, Perry DJ, Blanchfield JL, Posgai AL, Wiedeman AE, Diggins K, Rahman A, Tree TIM, Brusko TM, Levings MK, James EA, Kent SC, Speake C, Homann D, Long SA; Immunology of Diabetes Society T-Cell Cytometry Group. Yang JHM, et al. Among authors: diggins k. Eur J Immunol. 2022 Mar;52(3):372-388. doi: 10.1002/eji.202049067. Epub 2022 Jan 28. Eur J Immunol. 2022. PMID: 35025103 Free PMC article.

2

Exhausted-like CD8+ T cell phenotypes linked to C-peptide preservation in alefacept-treated T1D subjects.

Diggins KE, Serti E, Muir V, Rosasco M, Lu T, Balmas E, Nepom G, Long SA, Linsley PS. Diggins KE, et al. JCI Insight. 2021 Feb 8;6(3):e142680. doi: 10.1172/jci.insight.142680. JCI Insight. 2021. PMID: 33351781 Free PMC article. Clinical Trial.

3

IL-6-Driven pSTAT1 Response Is Linked to T Cell Features Implicated in Early Immune Dysregulation.

Lambert K, Diggins KE, Jones BE, Hundhausen C, Maerz MD, Hocking AM, Sanda S, Greenbaum CJ, Linsley PS, Cerosaletti K, Buckner JH. Lambert K, et al. Among authors: diggins ke. Front Immunol. 2022 Jul 13;13:935394. doi: 10.3389/fimmu.2022.935394. eCollection 2022. Front Immunol. 2022. PMID: 35911690 Free PMC article.

4

Methods for discovery and characterization of cell subsets in high dimensional mass cytometry data.

Diggins KE, Ferrell PB Jr, Irish JM. Diggins KE, et al. Methods. 2015 Jul 1;82:55-63. doi: 10.1016/j.ymeth.2015.05.008. Epub 2015 May 13. Methods. 2015. PMID: 25979346 Free PMC article.

5

High-Dimensional Analysis of Acute Myeloid Leukemia Reveals Phenotypic Changes in Persistent Cells during Induction Therapy.

Ferrell PB Jr, Diggins KE, Polikowsky HG, Mohan SR, Seegmiller AC, Irish JM. Ferrell PB Jr, et al. PLoS One. 2016 Apr 13;11(4):e0153207. doi: 10.1371/journal.pone.0153207. eCollection 2016. PLoS One. 2016. PMID: 27074138 Free PMC article.

6

Generating Quantitative Cell Identity Labels with Marker Enrichment Modeling (MEM).

Diggins KE, Gandelman JS, Roe CE, Irish JM. Diggins KE, et al. Curr Protoc Cytom. 2018 Jan 18;83:10.21.1-10.21.28. doi: 10.1002/cpcy.34. Curr Protoc Cytom. 2018. PMID: 29345329 Free PMC article.

7

Characterizing cell subsets using marker enrichment modeling.

Diggins KE, Greenplate AR, Leelatian N, Wogsland CE, Irish JM. Diggins KE, et al. Nat Methods. 2017 Mar;14(3):275-278. doi: 10.1038/nmeth.4149. Epub 2017 Jan 30. Nat Methods. 2017. PMID: 28135256 Free PMC article.

8

Characterizing Phenotypes and Signaling Networks of Single Human Cells by Mass Cytometry.

Leelatian N, Diggins KE, Irish JM. Leelatian N, et al. Methods Mol Biol. 2015;1346:99-113. doi: 10.1007/978-1-4939-2987-0_8. Methods Mol Biol. 2015. PMID: 26542718 Free PMC article.

9

IRF5 genetic risk variants drive myeloid-specific IRF5 hyperactivation and presymptomatic SLE.

Li D, Matta B, Song S, Nelson V, Diggins K, Simpfendorfer KR, Gregersen PK, Linsley P, Barnes BJ. Li D, et al. Among authors: diggins k. JCI Insight. 2020 Jan 30;5(2):e124020. doi: 10.1172/jci.insight.124020. JCI Insight. 2020. PMID: 31877114 Free PMC article.

10

Computational Immune Monitoring Reveals Abnormal Double-Negative T Cells Present across Human Tumor Types.

Greenplate AR, McClanahan DD, Oberholtzer BK, Doxie DB, Roe CE, Diggins KE, Leelatian N, Rasmussen ML, Kelley MC, Gama V, Siska PJ, Rathmell JC, Ferrell PB, Johnson DB, Irish JM. Greenplate AR, et al. Among authors: diggins ke. Cancer Immunol Res. 2019 Jan;7(1):86-99. doi: 10.1158/2326-6066.CIR-17-0692. Epub 2018 Nov 9. Cancer Immunol Res. 2019. PMID: 30413431 Free PMC article.

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