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Fasting improves therapeutic response in hepatocellular carcinoma through p53-dependent metabolic synergism.
Krstic J, Reinisch I, Schindlmaier K, Galhuber M, Riahi Z, Berger N, Kupper N, Moyschewitz E, Auer M, Michenthaler H, Nössing C, Depaoli MR, Ramadani-Muja J, Usluer S, Stryeck S, Pichler M, Rinner B, Deutsch AJA, Reinisch A, Madl T, Chiozzi RZ, Heck AJR, Huch M, Malli R, Prokesch A. Krstic J, et al. Among authors: madl t. Sci Adv. 2022 Jan 21;8(3):eabh2635. doi: 10.1126/sciadv.abh2635. Epub 2022 Jan 21. Sci Adv. 2022. PMID: 35061544 Free PMC article.
Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network.
Anvarian Z, Nojima H, van Kappel EC, Madl T, Spit M, Viertler M, Jordens I, Low TY, van Scherpenzeel RC, Kuper I, Richter K, Heck AJ, Boelens R, Vincent JP, Rüdiger SG, Maurice MM. Anvarian Z, et al. Among authors: madl t. Nat Struct Mol Biol. 2016 Apr;23(4):324-32. doi: 10.1038/nsmb.3191. Epub 2016 Mar 14. Nat Struct Mol Biol. 2016. PMID: 26974125
PRMT1-mediated methylation of MICU1 determines the UCP2/3 dependency of mitochondrial Ca(2+) uptake in immortalized cells.
Madreiter-Sokolowski CT, Klec C, Parichatikanond W, Stryeck S, Gottschalk B, Pulido S, Rost R, Eroglu E, Hofmann NA, Bondarenko AI, Madl T, Waldeck-Weiermair M, Malli R, Graier WF. Madreiter-Sokolowski CT, et al. Among authors: madl t. Nat Commun. 2016 Sep 19;7:12897. doi: 10.1038/ncomms12897. Nat Commun. 2016. PMID: 27642082 Free PMC article.
Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis.
Prokesch A, Graef FA, Madl T, Kahlhofer J, Heidenreich S, Schumann A, Moyschewitz E, Pristoynik P, Blaschitz A, Knauer M, Muenzner M, Bogner-Strauss JG, Dohr G, Schulz TJ, Schupp M. Prokesch A, et al. Among authors: madl t. FASEB J. 2017 Feb;31(2):732-742. doi: 10.1096/fj.201600845R. Epub 2016 Nov 3. FASEB J. 2017. PMID: 27811061 Free PMC article.
Because of its tumor suppressor function, p53 stabilization by starvation could have implications for both metabolic and oncological diseases of the liver.-Prokesch, A., Graef, F. A., Madl, T., Kahlhofer, J., Heidenreich, S., Schumann, A., Moyschewitz, E., Pristoyni …
Because of its tumor suppressor function, p53 stabilization by starvation could have implications for both metabolic and oncological disease …
Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo.
Bischof H, Rehberg M, Stryeck S, Artinger K, Eroglu E, Waldeck-Weiermair M, Gottschalk B, Rost R, Deak AT, Niedrist T, Vujic N, Lindermuth H, Prassl R, Pelzmann B, Groschner K, Kratky D, Eller K, Rosenkranz AR, Madl T, Plesnila N, Graier WF, Malli R. Bischof H, et al. Among authors: madl t. Nat Commun. 2017 Nov 10;8(1):1422. doi: 10.1038/s41467-017-01615-z. Nat Commun. 2017. PMID: 29127288 Free PMC article.
Acetate-free, citrate-acidified bicarbonate dialysis improves serum calcification propensity-a preliminary study.
Lorenz G, Mayer CC, Bachmann Q, Stryeck S, Braunisch MC, Haller B, Carbajo-Lozoya J, Schmidt A, Witthauer S, Abuzahu J, Kemmner S, Angermann S, Koneru N, Wassertheurer S, Bieber R, Heemann U, Madl T, Pasch A, Schmaderer C. Lorenz G, et al. Among authors: madl t. Nephrol Dial Transplant. 2018 Nov 1;33(11):2043-2051. doi: 10.1093/ndt/gfy134. Nephrol Dial Transplant. 2018. PMID: 29860419
Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting.
Alkan HF, Walter KE, Luengo A, Madreiter-Sokolowski CT, Stryeck S, Lau AN, Al-Zoughbi W, Lewis CA, Thomas CJ, Hoefler G, Graier WF, Madl T, Vander Heiden MG, Bogner-Strauss JG. Alkan HF, et al. Among authors: madl t. Cell Metab. 2018 Nov 6;28(5):706-720.e6. doi: 10.1016/j.cmet.2018.07.021. Epub 2018 Aug 16. Cell Metab. 2018. PMID: 30122555 Free PMC article.
Enhanced inter-compartmental Ca2+ flux modulates mitochondrial metabolism and apoptotic threshold during aging.
Madreiter-Sokolowski CT, Waldeck-Weiermair M, Bourguignon MP, Villeneuve N, Gottschalk B, Klec C, Stryeck S, Radulovic S, Parichatikanond W, Frank S, Madl T, Malli R, Graier WF. Madreiter-Sokolowski CT, et al. Among authors: madl t. Redox Biol. 2019 Jan;20:458-466. doi: 10.1016/j.redox.2018.11.003. Epub 2018 Nov 9. Redox Biol. 2019. PMID: 30458321 Free PMC article.
173 results