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The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2.
Stem Cell Reports. 2022 Feb 8;17(2):307-320. doi: 10.1016/j.stemcr.2021.12.011. Epub 2022 Jan 20.
Stem Cell Reports. 2022.
PMID: 35063125
Free PMC article.
Hydroxyethylstarch (130/0.4) tightens the blood-brain barrier in vitro.
Gerhartl A, Hahn K, Neuhoff A, Friedl HP, Förster CY, Wunder C, Schick M, Burek M, Neuhaus W.
Gerhartl A, et al.
Brain Res. 2020 Jan 15;1727:146560. doi: 10.1016/j.brainres.2019.146560. Epub 2019 Nov 20.
Brain Res. 2020.
PMID: 31756307
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The pivotal role of micro-environmental cells in a human blood-brain barrier in vitro model of cerebral ischemia: functional and transcriptomic analysis.
Gerhartl A, Pracser N, Vladetic A, Hendrikx S, Friedl HP, Neuhaus W.
Gerhartl A, et al.
Fluids Barriers CNS. 2020 Mar 5;17(1):19. doi: 10.1186/s12987-020-00179-3.
Fluids Barriers CNS. 2020.
PMID: 32138745
Free PMC article.
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A Microfluidic Multisize Spheroid Array for Multiparametric Screening of Anticancer Drugs and Blood-Brain Barrier Transport Properties.
Eilenberger C, Rothbauer M, Selinger F, Gerhartl A, Jordan C, Harasek M, Schädl B, Grillari J, Weghuber J, Neuhaus W, Küpcü S, Ertl P.
Eilenberger C, et al. Among authors: gerhartl a.
Adv Sci (Weinh). 2021 Jun;8(11):e2004856. doi: 10.1002/advs.202004856. Epub 2021 Mar 24.
Adv Sci (Weinh). 2021.
PMID: 34105271
Free PMC article.
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A Human Stem Cell-Derived Brain-Liver Chip for Assessing Blood-Brain-Barrier Permeation of Pharmaceutical Drugs.
Koenig L, Ramme AP, Faust D, Mayer M, Flötke T, Gerhartl A, Brachner A, Neuhaus W, Appelt-Menzel A, Metzger M, Marx U, Dehne EM.
Koenig L, et al. Among authors: gerhartl a.
Cells. 2022 Oct 19;11(20):3295. doi: 10.3390/cells11203295.
Cells. 2022.
PMID: 36291161
Free PMC article.
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Human isogenic cells of the neurovascular unit exert transcriptomic cell type-specific effects on a blood-brain barrier in vitro model of late-onset Alzheimer disease.
Haferkamp U, Hartmann C, Abid CL, Brachner A, Höchner A, Gerhartl A, Harwardt B, Leckzik S, Leu J, Metzger M, Nastainczyk-Wulf M, Neuhaus W, Oerter S, Pless O, Rujescu D, Jung M, Appelt-Menzel A.
Haferkamp U, et al. Among authors: gerhartl a.
Fluids Barriers CNS. 2023 Oct 31;20(1):78. doi: 10.1186/s12987-023-00471-y.
Fluids Barriers CNS. 2023.
PMID: 37907966
Free PMC article.
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Transport of Non-Steroidal Anti-Inflammatory Drugs across an Oral Mucosa Epithelium In Vitro Model.
Lin GC, Friedl HP, Grabner S, Gerhartl A, Neuhaus W.
Lin GC, et al. Among authors: gerhartl a.
Pharmaceutics. 2024 Apr 15;16(4):543. doi: 10.3390/pharmaceutics16040543.
Pharmaceutics. 2024.
PMID: 38675204
Free PMC article.
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Polycomb Protein Eed is Required for Neurogenesis and Cortical Injury Activation in the Subventricular Zone.
Sun B, Chang E, Gerhartl A, Szele FG.
Sun B, et al. Among authors: gerhartl a.
Cereb Cortex. 2018 Apr 1;28(4):1369-1382. doi: 10.1093/cercor/bhx289.
Cereb Cortex. 2018.
PMID: 29415247
Free PMC article.
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