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Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation.
Martin S, Tyrrell J, Thomas EL, Bown MJ, Wood AR, Beaumont RN, Tsoi LC, Stuart PE, Elder JT, Law P, Houlston R, Kabrhel C, Papadimitriou N, Gunter MJ, Bull CJ, Bell JA, Vincent EE, Sattar N, Dunlop MG, Tomlinson IPM, Lindström S; INVENT consortium; Bell JD, Frayling TM, Yaghootkar H. Martin S, et al. Among authors: vincent ee. Elife. 2022 Jan 25;11:e72452. doi: 10.7554/eLife.72452. Elife. 2022. PMID: 35074047 Free PMC article.
A Phenome-Wide Mendelian Randomization Study of Pancreatic Cancer Using Summary Genetic Data.
Langdon RJ, Richmond RC, Hemani G, Zheng J, Wade KH, Carreras-Torres R, Johansson M, Brennan P, Wootton RE, Munafo MR, Smith GD, Relton CL, Vincent EE, Martin RM, Haycock P. Langdon RJ, et al. Among authors: vincent ee. Cancer Epidemiol Biomarkers Prev. 2019 Dec;28(12):2070-2078. doi: 10.1158/1055-9965.EPI-19-0036. Epub 2019 Jul 17. Cancer Epidemiol Biomarkers Prev. 2019. PMID: 31315910
Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study.
Bull CJ, Bell JA, Murphy N, Sanderson E, Davey Smith G, Timpson NJ, Banbury BL, Albanes D, Berndt SI, Bézieau S, Bishop DT, Brenner H, Buchanan DD, Burnett-Hartman A, Casey G, Castellví-Bel S, Chan AT, Chang-Claude J, Cross AJ, de la Chapelle A, Figueiredo JC, Gallinger SJ, Gapstur SM, Giles GG, Gruber SB, Gsur A, Hampe J, Hampel H, Harrison TA, Hoffmeister M, Hsu L, Huang WY, Huyghe JR, Jenkins MA, Joshu CE, Keku TO, Kühn T, Kweon SS, Le Marchand L, Li CI, Li L, Lindblom A, Martín V, May AM, Milne RL, Moreno V, Newcomb PA, Offit K, Ogino S, Phipps AI, Platz EA, Potter JD, Qu C, Quirós JR, Rennert G, Riboli E, Sakoda LC, Schafmayer C, Schoen RE, Slattery ML, Tangen CM, Tsilidis KK, Ulrich CM, van Duijnhoven FJB, van Guelpen B, Visvanathan K, Vodicka P, Vodickova L, Wang H, White E, Wolk A, Woods MO, Wu AH, Campbell PT, Zheng W, Peters U, Vincent EE, Gunter MJ. Bull CJ, et al. Among authors: vincent ee. BMC Med. 2020 Dec 17;18(1):396. doi: 10.1186/s12916-020-01855-9. BMC Med. 2020. PMID: 33327948 Free PMC article.
Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study.
Gormley M, Yarmolinsky J, Dudding T, Burrows K, Martin RM, Thomas S, Tyrrell J, Brennan P, Pring M, Boccia S, Olshan AF, Diergaarde B, Hung RJ, Liu G, Legge D, Tajara EH, Severino P, Lacko M, Ness AR, Davey Smith G, Vincent EE, Richmond RC. Gormley M, et al. Among authors: vincent ee. PLoS Genet. 2021 Apr 22;17(4):e1009525. doi: 10.1371/journal.pgen.1009525. eCollection 2021 Apr. PLoS Genet. 2021. PMID: 33886544 Free PMC article.
Cholesterol Auxotrophy as a Targetable Vulnerability in Clear Cell Renal Cell Carcinoma.
Riscal R, Bull CJ, Mesaros C, Finan JM, Carens M, Ho ES, Xu JP, Godfrey J, Brennan P, Johansson M, Purdue MP, Chanock SJ, Mariosa D, Timpson NJ, Vincent EE, Keith B, Blair IA, Skuli N, Simon MC. Riscal R, et al. Among authors: vincent ee. Cancer Discov. 2021 Dec 1;11(12):3106-3125. doi: 10.1158/2159-8290.CD-21-0211. Cancer Discov. 2021. PMID: 34244212 Free PMC article.
77 results