Leung K - Search Results

1

CD97 is associated with mitogenic pathway activation, metabolic reprogramming, and immune microenvironment changes in glioblastoma.

Safaee MM, Wang EJ, Jain S, Chen JS, Gill S, Zheng AC, Garcia JH, Beniwal AS, Tran Y, Nguyen AT, Trieu M, Leung K, Wells J, Maclean JM, Wycoff K, Aghi MK. Safaee MM, et al. Among authors: leung k. Sci Rep. 2022 Jan 27;12(1):1464. doi: 10.1038/s41598-022-05259-y. Sci Rep. 2022. PMID: 35087132 Free PMC article.

2

Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma.

Nejo T, Wang L, Leung KK, Wang A, Lakshmanachetty S, Gallus M, Kwok DW, Hong C, Chen LH, Carrera DA, Zhang MY, Stevers NO, Maldonado GC, Yamamichi A, Watchmaker PB, Naik A, Shai A, Phillips JJ, Chang SM, Wiita AP, Wells JA, Costello JF, Diaz AA, Okada H. Nejo T, et al. Among authors: leung kk. Sci Rep. 2024 Mar 16;14(1):6362. doi: 10.1038/s41598-024-56684-0. Sci Rep. 2024. PMID: 38493204 Free PMC article.

3

Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes.

Leung KK, Wilson GM, Kirkemo LL, Riley NM, Coon JJ, Wells JA. Leung KK, et al. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7764-7775. doi: 10.1073/pnas.1917947117. Epub 2020 Mar 23. Proc Natl Acad Sci U S A. 2020. PMID: 32205440 Free PMC article.

4

Large remodeling of the Myc-induced cell surface proteome in B cells and prostate cells creates new opportunities for immunotherapy.

Chen W, Mou KY, Solomon P, Aggarwal R, Leung KK, Wells JA. Chen W, et al. Among authors: leung kk. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2018861118. doi: 10.1073/pnas.2018861118. Proc Natl Acad Sci U S A. 2021. PMID: 33483421 Free PMC article.

5

Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers.

Lim SA, Zhou J, Martinko AJ, Wang YH, Filippova EV, Steri V, Wang D, Remesh SG, Liu J, Hann B, Kossiakoff AA, Evans MJ, Leung KK, Wells JA. Lim SA, et al. Among authors: leung kk. J Clin Invest. 2022 Feb 15;132(4):e154604. doi: 10.1172/JCI154604. J Clin Invest. 2022. PMID: 35166238 Free PMC article.

6

The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance.

Ferguson ID, Patiño-Escobar B, Tuomivaara ST, Lin YT, Nix MA, Leung KK, Kasap C, Ramos E, Nieves Vasquez W, Talbot A, Hale M, Naik A, Kishishita A, Choudhry P, Lopez-Girona A, Miao W, Wong SW, Wolf JL, Martin TG 3rd, Shah N, Vandenberg S, Prakash S, Besse L, Driessen C, Posey AD Jr, Mullins RD, Eyquem J, Wells JA, Wiita AP. Ferguson ID, et al. Among authors: leung kk. Nat Commun. 2022 Jul 15;13(1):4121. doi: 10.1038/s41467-022-31810-6. Nat Commun. 2022. PMID: 35840578 Free PMC article.

7

Theranostic Targeting of CUB Domain Containing Protein 1 (CDCP1) in Pancreatic Cancer.

Moroz A, Wang YH, Sharib JM, Wei J, Zhao N, Huang Y, Chen Z, Martinko AJ, Zhuo J, Lim SA, Zhang LH, Seo Y, Carlin S, Leung KK, Collisson EA, Kirkwood KS, Wells JA, Evans MJ. Moroz A, et al. Among authors: leung kk. Clin Cancer Res. 2020 Jul 15;26(14):3608-3615. doi: 10.1158/1078-0432.CCR-20-0268. Epub 2020 Apr 27. Clin Cancer Res. 2020. PMID: 32341034 Free PMC article.

8

CUB Domain-Containing Protein 1 (CDCP1) Is a Target for Radioligand Therapy in Castration-Resistant Prostate Cancer, including PSMA Null Disease.

Zhao N, Chopra S, Trepka K, Wang YH, Sakhamuri S, Hooshdaran N, Kim H, Zhou J, Lim SA, Leung KK, Egusa EA, Zhu J, Zhang L, Foye A, Sriram R, Chan E, Seo Y, Feng FY, Small EJ, Chou J, Wells JA, Aggarwal R, Evans MJ. Zhao N, et al. Among authors: leung kk. Clin Cancer Res. 2022 Jul 15;28(14):3066-3075. doi: 10.1158/1078-0432.CCR-21-3858. Clin Cancer Res. 2022. PMID: 35604681 Free PMC article.

9

Multiomics of azacitidine-treated AML cells reveals variable and convergent targets that remodel the cell-surface proteome.

Leung KK, Nguyen A, Shi T, Tang L, Ni X, Escoubet L, MacBeth KJ, DiMartino J, Wells JA. Leung KK, et al. Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):695-700. doi: 10.1073/pnas.1813666116. Epub 2018 Dec 24. Proc Natl Acad Sci U S A. 2019. PMID: 30584089 Free PMC article.

10

Profiling the Surfaceome Identifies Therapeutic Targets for Cells with Hyperactive mTORC1 Signaling.

Wei J, Leung K, Truillet C, Ruggero D, Wells JA, Evans MJ. Wei J, et al. Among authors: leung k. Mol Cell Proteomics. 2020 Feb;19(2):294-307. doi: 10.1074/mcp.RA119.001785. Epub 2019 Dec 2. Mol Cell Proteomics. 2020. PMID: 31792071 Free PMC article.

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