Wells J - Search Results

1

CD97 is associated with mitogenic pathway activation, metabolic reprogramming, and immune microenvironment changes in glioblastoma.

Safaee MM, Wang EJ, Jain S, Chen JS, Gill S, Zheng AC, Garcia JH, Beniwal AS, Tran Y, Nguyen AT, Trieu M, Leung K, Wells J, Maclean JM, Wycoff K, Aghi MK. Safaee MM, et al. Among authors: wells j. Sci Rep. 2022 Jan 27;12(1):1464. doi: 10.1038/s41598-022-05259-y. Sci Rep. 2022. PMID: 35087132 Free PMC article.

2

Engineering Improved Antiphosphotyrosine Antibodies Based on an Immunoconvergent Binding Motif.

Mou Y, Zhou XX, Leung K, Martinko AJ, Yu JY, Chen W, Wells JA. Mou Y, et al. Among authors: wells ja. J Am Chem Soc. 2018 Dec 5;140(48):16615-16624. doi: 10.1021/jacs.8b08402. Epub 2018 Nov 19. J Am Chem Soc. 2018. PMID: 30398859

3

Multiomics of azacitidine-treated AML cells reveals variable and convergent targets that remodel the cell-surface proteome.

Leung KK, Nguyen A, Shi T, Tang L, Ni X, Escoubet L, MacBeth KJ, DiMartino J, Wells JA. Leung KK, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):695-700. doi: 10.1073/pnas.1813666116. Epub 2018 Dec 24. Proc Natl Acad Sci U S A. 2019. PMID: 30584089 Free PMC article.

4

Profiling the Surfaceome Identifies Therapeutic Targets for Cells with Hyperactive mTORC1 Signaling.

Wei J, Leung K, Truillet C, Ruggero D, Wells JA, Evans MJ. Wei J, et al. Among authors: wells ja. Mol Cell Proteomics. 2020 Feb;19(2):294-307. doi: 10.1074/mcp.RA119.001785. Epub 2019 Dec 2. Mol Cell Proteomics. 2020. PMID: 31792071 Free PMC article.

5

Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes.

Leung KK, Wilson GM, Kirkemo LL, Riley NM, Coon JJ, Wells JA. Leung KK, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7764-7775. doi: 10.1073/pnas.1917947117. Epub 2020 Mar 23. Proc Natl Acad Sci U S A. 2020. PMID: 32205440 Free PMC article.

6

Theranostic Targeting of CUB Domain Containing Protein 1 (CDCP1) in Pancreatic Cancer.

Moroz A, Wang YH, Sharib JM, Wei J, Zhao N, Huang Y, Chen Z, Martinko AJ, Zhuo J, Lim SA, Zhang LH, Seo Y, Carlin S, Leung KK, Collisson EA, Kirkwood KS, Wells JA, Evans MJ. Moroz A, et al. Among authors: wells ja. Clin Cancer Res. 2020 Jul 15;26(14):3608-3615. doi: 10.1158/1078-0432.CCR-20-0268. Epub 2020 Apr 27. Clin Cancer Res. 2020. PMID: 32341034 Free PMC article.

7

Deep profiling of protease substrate specificity enabled by dual random and scanned human proteome substrate phage libraries.

Zhou J, Li S, Leung KK, O'Donovan B, Zou JY, DeRisi JL, Wells JA. Zhou J, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25464-25475. doi: 10.1073/pnas.2009279117. Epub 2020 Sep 24. Proc Natl Acad Sci U S A. 2020. PMID: 32973096 Free PMC article.

8

Large remodeling of the Myc-induced cell surface proteome in B cells and prostate cells creates new opportunities for immunotherapy.

Chen W, Mou KY, Solomon P, Aggarwal R, Leung KK, Wells JA. Chen W, et al. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2018861118. doi: 10.1073/pnas.2018861118. Proc Natl Acad Sci U S A. 2021. PMID: 33483421 Free PMC article.

9

Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers.

Lim SA, Zhou J, Martinko AJ, Wang YH, Filippova EV, Steri V, Wang D, Remesh SG, Liu J, Hann B, Kossiakoff AA, Evans MJ, Leung KK, Wells JA. Lim SA, et al. Among authors: wells ja. J Clin Invest. 2022 Feb 15;132(4):e154604. doi: 10.1172/JCI154604. J Clin Invest. 2022. PMID: 35166238 Free PMC article.

10

Discovery Proteomics Analysis Determines That Driver Oncogenes Suppress Antiviral Defense Pathways Through Reduction in Interferon-β Autocrine Stimulation.

Solomon PE, Kirkemo LL, Wilson GM, Leung KK, Almond MH, Sayles LC, Sweet-Cordero EA, Rosenberg OS, Coon JJ, Wells JA. Solomon PE, et al. Among authors: wells ja. Mol Cell Proteomics. 2022 Jul;21(7):100247. doi: 10.1016/j.mcpro.2022.100247. Epub 2022 May 18. Mol Cell Proteomics. 2022. PMID: 35594991 Free PMC article.

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