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207 results

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Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules.
Stravalaci M, Pagani I, Paraboschi EM, Pedotti M, Doni A, Scavello F, Mapelli SN, Sironi M, Perucchini C, Varani L, Matkovic M, Cavalli A, Cesana D, Gallina P, Pedemonte N, Capurro V, Clementi N, Mancini N, Invernizzi P, Bayarri-Olmos R, Garred P, Rappuoli R, Duga S, Bottazzi B, Uguccioni M, Asselta R, Vicenzi E, Mantovani A, Garlanda C. Stravalaci M, et al. Among authors: uguccioni m. Nat Immunol. 2022 Feb;23(2):275-286. doi: 10.1038/s41590-021-01114-w. Epub 2022 Jan 31. Nat Immunol. 2022. PMID: 35102342
Reply to: Hultström et al., Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19. Mannose-binding lectin genetics in COVID-19.
Asselta R, Paraboschi EM, Stravalaci M, Invernizzi P, Bonfanti P, Biondi A, Pagani I, Pedotti M, Doni A, Scavello F, Mapelli SN, Sironi M, Perucchini C, Varani L, Matkovic M, Cavalli A, Cesana D, Gallina P, Pedemonte N, Capurro V, Clementi N, Mancini N, Bayarri-Olmos R, Garred P, Rappuoli R, Duga S, Bottazzi B, Uguccioni M, Vicenzi E, Mantovani A, Garlanda C. Asselta R, et al. Among authors: uguccioni m. Nat Immunol. 2022 Jun;23(6):865-867. doi: 10.1038/s41590-022-01228-9. Epub 2022 May 27. Nat Immunol. 2022. PMID: 35624207 No abstract available.
Molecular Signatures of Immunity and Immunogenicity in Infection and Vaccination.
Haks MC, Bottazzi B, Cecchinato V, De Gregorio C, Del Giudice G, Kaufmann SHE, Lanzavecchia A, Lewis DJM, Maertzdorf J, Mantovani A, Sallusto F, Sironi M, Uguccioni M, Ottenhoff THM. Haks MC, et al. Among authors: uguccioni m. Front Immunol. 2017 Nov 15;8:1563. doi: 10.3389/fimmu.2017.01563. eCollection 2017. Front Immunol. 2017. PMID: 29204145 Free PMC article. Review.
Systematic Development of Peptide Inhibitors Targeting the CXCL12/HMGB1 Interaction.
Sgrignani J, Cecchinato V, Fassi EMA, D'Agostino G, Garofalo M, Danelon G, Pedotti M, Simonelli L, Varani L, Grazioso G, Uguccioni M, Cavalli A. Sgrignani J, et al. Among authors: uguccioni m. J Med Chem. 2021 Sep 23;64(18):13439-13450. doi: 10.1021/acs.jmedchem.1c00852. Epub 2021 Sep 12. J Med Chem. 2021. PMID: 34510899 Free article.
HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4.
Schiraldi M, Raucci A, Muñoz LM, Livoti E, Celona B, Venereau E, Apuzzo T, De Marchis F, Pedotti M, Bachi A, Thelen M, Varani L, Mellado M, Proudfoot A, Bianchi ME, Uguccioni M. Schiraldi M, et al. Among authors: uguccioni m. J Exp Med. 2012 Mar 12;209(3):551-63. doi: 10.1084/jem.20111739. Epub 2012 Feb 27. J Exp Med. 2012. PMID: 22370717 Free PMC article.
Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release.
Venereau E, Casalgrandi M, Schiraldi M, Antoine DJ, Cattaneo A, De Marchis F, Liu J, Antonelli A, Preti A, Raeli L, Shams SS, Yang H, Varani L, Andersson U, Tracey KJ, Bachi A, Uguccioni M, Bianchi ME. Venereau E, et al. Among authors: uguccioni m. J Exp Med. 2012 Aug 27;209(9):1519-28. doi: 10.1084/jem.20120189. Epub 2012 Aug 6. J Exp Med. 2012. PMID: 22869893 Free PMC article.
207 results