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Reduced Acrolein Detoxification in akr1a1a Zebrafish Mutants Causes Impaired Insulin Receptor Signaling and Microvascular Alterations.
Qi H, Schmöhl F, Li X, Qian X, Tabler CT, Bennewitz K, Sticht C, Morgenstern J, Fleming T, Volk N, Hausser I, Heidenreich E, Hell R, Nawroth PP, Kroll J. Qi H, et al. Among authors: nawroth pp. Adv Sci (Weinh). 2021 Sep;8(18):e2101281. doi: 10.1002/advs.202101281. Epub 2021 Jul 18. Adv Sci (Weinh). 2021. PMID: 34278746 Free PMC article.
CNDP1 knockout in zebrafish alters the amino acid metabolism, restrains weight gain, but does not protect from diabetic complications.
Schmöhl F, Peters V, Schmitt CP, Poschet G, Büttner M, Li X, Weigand T, Poth T, Volk N, Morgenstern J, Fleming T, Nawroth PP, Kroll J. Schmöhl F, et al. Among authors: nawroth pp. Cell Mol Life Sci. 2019 Nov;76(22):4551-4568. doi: 10.1007/s00018-019-03127-z. Epub 2019 May 9. Cell Mol Life Sci. 2019. PMID: 31073745 Free PMC article.
The combination of loss of glyoxalase1 and obesity results in hyperglycemia.
Lodd E, Wiggenhauser LM, Morgenstern J, Fleming TH, Poschet G, Büttner M, Tabler CT, Wohlfart DP, Nawroth PP, Kroll J. Lodd E, et al. Among authors: nawroth pp. JCI Insight. 2019 Jun 20;4(12):e126154. doi: 10.1172/jci.insight.126154. eCollection 2019 Jun 20. JCI Insight. 2019. PMID: 31217350 Free PMC article.
Regulation of Gluconeogenesis by Aldo-keto-reductase 1a1b in Zebrafish.
Li X, Schmöhl F, Qi H, Bennewitz K, Tabler CT, Poschet G, Hell R, Volk N, Poth T, Hausser I, Morgenstern J, Fleming T, Nawroth PP, Kroll J. Li X, et al. Among authors: nawroth pp. iScience. 2020 Nov 3;23(12):101763. doi: 10.1016/j.isci.2020.101763. eCollection 2020 Dec 18. iScience. 2020. PMID: 33251496 Free PMC article.
600 results